Evidence map›Paper›PMID 27235210›Full record

ReviewClinics in perinatology2016

Bilirubin-Induced Audiologic Injury in Preterm Infants.

Cristen Olds, John S Oghalai

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in perinatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Bilirubin kinetics in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Monitoring neonates for ototoxicity.International journal of audiology · 2018
    Review
  8. Clinical role of electrocochleography in children with auditory neuropathy spectrum disorder.International journal of pediatric otorhinolaryngology · 2017
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Cristen OldsDepartment of Otolaryngology - Head and Neck Surgery, Stanford University, 801 Welch Road, CA 94305, USA.
John S OghalaiDepartment of Otolaryngology - Head and Neck Surgery, Stanford University, 801 Welch Road, CA 94305, USA. Electronic address: joghalai@stanford.edu.
Stanford University · US

Funding

Outcomes in Children with Developmental Delay and Deafness: a Randomized TrialR01DC010075 · NIDCD · STANFORD UNIVERSITY · PI OGHALAI, JOHN S · 2009 to 2013
$2.0M
Translation of near-infrared spectroscopy for use in clinical neuro-imaging R56DC010164 · NIDCD · STANFORD UNIVERSITY · PI OGHALAI, JOHN S · 2010 to 2010
$420k
NIDCD NIH HHS R01 DC010075NIDCD NIH HHS R56 DC010164
6 · The paper itself

Abstract

Although hyperbilirubinemia is extremely common among neonates and is usually mild and transient, it sometimes leads to bilirubin-induced neurologic damage (BIND). The auditory pathway is highly sensitive to the effects of elevated total serum/plasma bilirubin (TB) levels, with damage manifesting clinically as auditory neuropathy spectrum disorder. Compared to full-term neonates, preterm neonates are more susceptible to BIND and suffer adverse effects at lower TB levels with worse long-term outcomes. Furthermore, although standardized guidelines for management of hyperbilirubinemia exist for term and late preterm neonates, similar guidelines for neonates less than 35 weeks gestational age are limited.

Indexed as

Cochlear NerveCochlear NucleusEvoked Potentials, Auditory, Brain StemHearing Loss, CentralHumansHyperbilirubinemia, NeonatalInfant, NewbornInfant, PrematureKernicterusAuditory brainstem responseAuditory neuropathyBilirubinCochleaCochlear nucleusHyperbilirubinemiaKernicterusPreterm

Identifiers

PMID27235210
PMCPMC4884602
OpenAlexW2286789687

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.