Evidence map›Paper›PMID 27235084›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2016

Measles immunity among pregnant women aged 15-44 years in Namibia, 2008 and 2010.

Cristina V Cardemil, Anna Jonas, Anita Beukes, Raydel Anderson, Paul A Rota, Bettina Bankamp, Howard E Gary, Souleymane Sawadogo, Sadhna V Patel, Sikota Zeko and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Cristina V CardemilCenters for Disease Control and Prevention, Global Immunization Division, 1600 Clifton Road, NE, Atlanta, GA 30333, USA. Electronic address: iyk8@cdc.gov.
Anna JonasMinistry of Health and Social Services, Directorate of Special Programmes, Primary Health Directorate, and Family Health Division (Expanded Programme on Immunizations), Windhoek, Namibia.
Anita BeukesCenters for Disease Control and Prevention, Windhoek, Namibia.
Raydel AndersonCenters for Disease Control and Prevention, Division of Viral Diseases, Atlanta, GA, USA.
Paul A RotaCenters for Disease Control and Prevention, Division of Viral Diseases, Atlanta, GA, USA.
Bettina BankampCenters for Disease Control and Prevention, Division of Viral Diseases, Atlanta, GA, USA.
Howard E GaryMinistry of Health and Social Services, Directorate of Special Programmes, Primary Health Directorate, and Family Health Division (Expanded Programme on Immunizations), Windhoek, Namibia.
Souleymane SawadogoCenters for Disease Control and Prevention, Windhoek, Namibia.
Sadhna V PatelCenters for Disease Control and Prevention, Windhoek, Namibia.
Sikota ZekoMinistry of Health and Social Services, Directorate of Special Programmes, Primary Health Directorate, and Family Health Division (Expanded Programme on Immunizations), Windhoek, Namibia.
Clementine MurouaMinistry of Health and Social Services, Directorate of Special Programmes, Primary Health Directorate, and Family Health Division (Expanded Programme on Immunizations), Windhoek, Namibia.
Esegiel GaebNamibia Institute of Pathology, Windhoek, Namibia.
Kathleen WannemuehlerCenters for Disease Control and Prevention, Global Immunization Division, 1600 Clifton Road, NE, Atlanta, GA 30333, USA.
Sue GerberCenters for Disease Control and Prevention, Windhoek, Namibia.
James L GoodsonCenters for Disease Control and Prevention, Global Immunization Division, 1600 Clifton Road, NE, Atlanta, GA 30333, USA.
Centers for Disease Control and Prevention · USMinistry of Health and Social Services · NANamibia Institute of Pathology · NA

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundNamibia experienced a large measles outbreak starting in 2009, with 38% of reported cases in adults, including women of reproductive age. Population immunity was assessed among pregnant women to determine whether immunization activities were needed in adults to achieve measles elimination in Namibia.

methodsA total of 1708 and 2040 specimens sampled from Namibian pregnant women aged 15-44 years who were included in the 2008 and 2010 National HIV Sentinel Survey, respectively, were tested for measles immunoglobulin G antibody. The proportion of women seropositive overall and by 5-year age strata was determined, and factors associated with seropositivity were analyzed by logistic regression, including age, facility type, gravidity, HIV status, and urban/rural setting. Seropositivity in 2008 versus 2010 was compared.

resultsIn both analysis years, measles seropositivity was lower in 15-19-year-olds (77%) and 20-24-year-olds (85-87%) and higher in 25-44-year-olds (90-94%) (2008, p<0.001; 2010, p<0.001). Overall measles seropositivity did not differ between 2008 (87%) and 2010 (87%) (p=0.7). HIV status did not affect seropositivity.

conclusionsLate in a large measles outbreak, 13% of pregnant women in Namibia, and almost one in four 15-19-year-old pregnant women, remained susceptible to measles. In Namibia, immunization campaigns with measles-containing vaccine should be considered for adults.

Indexed as

AdolescentAdultAntibodies, ViralFemaleHumansImmunizationImmunoglobulin GMaleMeaslesMeasles VaccineNamibiaPregnancyYoung AdultAntibodies, ViralImmunoglobulin GMeasles VaccineMeaslesNamibiaPopulation immunityPregnant womenSeroprevalence

Identifiers

PMID27235084
PMCPMC6996213
OpenAlexW2396181094

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.