ArticleBMC cardiovascular disorders2016
Geometrical and functional changes of left heart in adults with prehypertension and hypertension: a cross-sectional study from China.
Article in BMC cardiovascular disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Association of depression with hypertensive left ventricular hypertrophy in age, sex, and education level-specific differences.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Sex-Specific Associations of Anxiety With Left Ventricular Hypertrophy and Transmural Dispersion of Repolarization in Hypertensive Patients.Frontiers in cardiovascular medicine · 2022Article
- Article
- A narrative review of prehypertension and the cardiovascular system: effects and potential pathogenic mechanisms.Annals of translational medicine · 2021Review
- Effect of serum electrolytes within normal ranges on QTc prolongation: a cross-sectional study in a Chinese rural general population.BMC cardiovascular disorders · 2018Article
- The impact of nontraditional lipid profiles on left ventricular geometric abnormalities in general Chinese population.BMC cardiovascular disorders · 2018Article
- Gender-specific contribution of cardiometabolic index and lipid accumulation product to left ventricular geometry change in general population of rural China.BMC cardiovascular disorders · 2018Article
- Impact of hypertension with or without diabetes on left ventricular remodeling in rural Chinese population: a cross-sectional study.BMC cardiovascular disorders · 2017Article
- Observational
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Abstract
backgroundStudies regarding the association between prehypertension and the structual changes of left heart are scanty. However, which type of the geometrical change of left heart is predominated one in prehypertension and hypertension is controversial. It is therefore important to investigate geometrical and functional changes of left heart in adults with prehypertension and hypertension because of their prognostic significance.
methodsThe study was based on a cross-sectional design, a total of 10547 participants were classified into normotension group, prehypertension group and hypertension group. We analyzed clinical characteristics, echocardiographic parameters and distribution of left ventricular (LV) geometrical patterns in different groups.
resultsParticipants with prehypertension had higher values of most of echocardiographic parameters than those with normotension. The prevalence of left ventricular hypertrophy(LVH) was statistically different among three groups (P <0.001), and the rates of LVH in the three groups were 5.9, 8.6, 28.4 % by indexation to height(2.7) and 4.9, 5.3, 19.3 % by indexation to BSA, respectively. The prevalence rates of eccentric hypertrophy, concentric remodeling and concentric hypertrophy were 7.3 %, 5.3 % and 1.4 % in prehypertension group, and 17.8 %, 8.8 % and 10.6 % in hypertension group. Logistic regression analysis showed that systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean artery pressure (MAP) were all independent risk factors for left cardiac structural changes, and pulse pressure (PP) was independent risk factor for concentric and eccentric hypertrophy. Among four indices, DBP levels with OR values of 1.192, 1.759 and 1.278 were the strongest indicator for concentric remodeling, concentric hypertrophy and eccentric hypertrophy, respectively (P <0.001).
conclusionsThere exists LV geometrical change in adults with prehypertension and hypertension in rural Chinese population, and the eccentric hypertrophy was the highest proportion of geometric alterations. SBP, DBP, MAP and PP were all positively associated with left cardiac structural changes, and the association of DBP was the strongest.
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