Evidence map›Paper›PMID 27234593›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2016

Survey of laboratory-acquired infections around the world in biosafety level 3 and 4 laboratories.

N Wurtz, A Papa, M Hukic, A Di Caro, I Leparc-Goffart, E Leroy, M P Landini, Z Sekeyova, J S Dumler, D Bădescu and 8 more

Abstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Surveillance of laboratory exposures to human pathogens and toxins, Canada, 2024.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  6. Article
  7. Unmet Expectations: Life Scientists' Views on Biorisk and Responsibility.Applied biosafety : journal of the American Biological Safety Association · 2025
    Article
  8. [Laboratory Biosafety Guideline (2025) Revision].Jugan geon-gang gwa jilbyeong · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Biosafety, biosecurity, and bioethics.Monash bioethics review · 2024
    Review
  14. Canadian laboratory incidents with human pathogens and toxins: An overview of reports, 2016-2022.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article
  15. Article
  16. Non-vaccinal prophylaxis of tularemia.Frontiers in microbiology · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory-Applied biosafety : journal of the American Biological Safety Association · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

N WurtzURMITE, CNRS UMR 7278, IRD 198, Inserm 1095, Aix Marseille Université, IHU Méditerranée Infection, 27 bd Jean Moulin, 13005, Marseille, France.
A PapaDepartment of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
M HukicInternational Burch University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
A Di CaroNational Institute for Infectious Diseases L. Spallanzani, Rome, Italy.
I Leparc-GoffartERRIT-IRBA, HIA Laveran, Centre National de Référence des Arboviroses, 13384, Marseille, France.
E LeroyLaboratoire MiVEGEC, UMR IRD 224 CNRS 5290 UMI, 911 Av. Agropolis, 34394, Montpellier Cedex 5, France.
M P LandiniUnit of Clinical Microbiology, Regional Reference Centre for Microbiological Emergencies (CRREM), St Orsola-Malpighi University Hospital, Bologna, Italy.
Z SekeyovaInstitute of Virology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05, Bratislava, Slovak Republic.
J S DumlerDepartments of Pathology and Microbiology & Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.
D BădescuCantacuzino National Institute of Research, Bucharest, Romania.
N BusquetsIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
A CalistriDepartment of Molecular Medicine, University of Padova, Via Gabelli 63, 35100, Padova, Italy.
C ParolinDepartment of Molecular Medicine, University of Padova, Via Gabelli 63, 35100, Padova, Italy.
G PalùDepartment of Molecular Medicine, University of Padova, Via Gabelli 63, 35100, Padova, Italy.
I ChristovaDepartment of Microbiology, National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria.
M MaurinCentre National de Référence des Francisella, Laboratoire de Bactériologie, Département des Agents Infectieux, Institut de Biologie et Pathologie, Centre Hospitalier Universitaire de Grenoble, Université Joseph Fourier, Grenoble, France.
B La ScolaURMITE, CNRS UMR 7278, IRD 198, Inserm 1095, Aix Marseille Université, IHU Méditerranée Infection, 27 bd Jean Moulin, 13005, Marseille, France.
D RaoultURMITE, CNRS UMR 7278, IRD 198, Inserm 1095, Aix Marseille Université, IHU Méditerranée Infection, 27 bd Jean Moulin, 13005, Marseille, France. didier.raoult@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laboratory-acquired infections due to a variety of bacteria, viruses, parasites, and fungi have been described over the last century, and laboratory workers are at risk of exposure to these infectious agents. However, reporting laboratory-associated infections has been largely voluntary, and there is no way to determine the real number of people involved or to know the precise risks for workers. In this study, an international survey based on volunteering was conducted in biosafety level 3 and 4 laboratories to determine the number of laboratory-acquired infections and the possible underlying causes of these contaminations. The analysis of the survey reveals that laboratory-acquired infections have been infrequent and even rare in recent years, and human errors represent a very high percentage of the cases. Today, most risks from biological hazards can be reduced through the use of appropriate procedures and techniques, containment devices and facilities, and the training of personnel.

Indexed as

Biomedical ResearchLaboratoriesOccupational DiseasesOccupational ExposureContainment of BiohazardsCross-Sectional StudiesHumansPersonal Protective EquipmentRisk AssessmentSafetySurveys and Questionnaires

Identifiers

PMID27234593
PMCPMC7088173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.