Evidence map›Paper›PMID 27234432›Full record

Observational studyBMC oral health2016

Pain levels and typical symptoms of acute endodontic infections: a prospective, observational study.

Dan-Krister Rechenberg, Ulrike Held, Jakob M Burgstaller, Gabriel Bosch, Thomas Attin

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC oral health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04787731 (Efficacy of Two Dental Local Anesthetics on the Oral Health-Related Quality of Life After Endodontic Treatment in the Symptomatic Mandibular Molars), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04787731 phase4suspendednot on this mapstarted 2019, after this paper: background citation

Efficacy of Two Dental Local Anesthetics on the Oral Health-Related Quality of Life After Endodontic Treatment in the Symptomatic Mandibular Molars: A Double Blind Randomized Controlled Trial

TypeinterventionalSponsorNYU College of DentistryRan2019 to 2024Enrolled100ConditionsPain, Postoperative, Quality of LifeArmsBupivacaine Local Anesthetic
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dan-Krister RechenbergDepartment of Preventive Dentistry, Periodontology and Cariology, Center of Dental Medicine, University of Zürich, Switzerland, Plattenstrasse 11, CH-8032, Zürich, Switzerland. dan.rechenberg@zzm.uzh.ch.
Ulrike HeldDepartment of Internal Medicine, Horten Center for Patient Oriented Research and Knowledge Transfer, University of Zürich, Zürich, Switzerland.
Jakob M BurgstallerDepartment of Internal Medicine, Horten Center for Patient Oriented Research and Knowledge Transfer, University of Zürich, Zürich, Switzerland.
Gabriel BoschDepartment of Preventive Dentistry, Periodontology and Cariology, Center of Dental Medicine, University of Zürich, Switzerland, Plattenstrasse 11, CH-8032, Zürich, Switzerland.
Thomas AttinDepartment of Preventive Dentistry, Periodontology and Cariology, Center of Dental Medicine, University of Zürich, Switzerland, Plattenstrasse 11, CH-8032, Zürich, Switzerland.
University of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to identify key symptoms that could be associated with the diagnosis of acute forms of symptomatic apical periodontitis (SAP) and symptomatic irreversible pulpitis (SIP), and to identify a diagnostic algorithm based on these symptoms.

methodsIn this prospective, observational study 173 emergency patients diagnosed with acute pain of endodontic origin and no swelling or fistula were included. Patients were asked 11 specific questions from a checklist with a possible discerning value between acute SAP and acute SIP. Pain levels were recorded using the numeric rating scale (NRS-11). Subsequently, the painful tooth was diagnosed. Logistic regression was used to evaluate the checklist regarding its differentiation between SAP (N = 103) and SIP (N = 70). Moreover, a decision tree was constructed based on recursive partitioning to identify a hierarchy in differentiating symptoms.

resultsWith identical median NRS-11 scores of 8, the teeth diagnosed with acute SAP and SIP were severely painful. The decision tree analysis resulted in a tree with splits according to pain on cold, perceived tooth extrusion, and pain duration. The overall sensitivity of the tree to detect SAP based on key symptoms was 95 %, its specificity was 31 %.

conclusionsThe best indicator for SAP was a reported absence of pain to cold stimuli. In teeth that did have a history of pain triggered by cold stimuli, the decision tree correctly identified SAP in 72 % of the teeth that felt too high and had hurt for less than one week.

Indexed as

HumansPainPain MeasurementPeriapical PeriodontitisProspective StudiesPulpitisDiagnosticPainRoot canalSymptom

Identifiers

PMID27234432
PMCPMC4884369
OpenAlexW2398015855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.