Evidence map›Paper›PMID 27234385›Full record

ArticleTranslational respiratory medicine2013

Blood viscosity as a forgotten factor and its effect on pulmonary flow.

Gulfidan Cakmak, Fatma Ates Alkan, Kazim Korkmaz, Zuhal Aydan Saglam, Denizhan Karis, Mustafa Yenigun, Meltem Ercan

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Article in Translational respiratory medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gulfidan CakmakDepartment of Chest Disease, Haseki Training and Research Hospital, Millet St Fatih, Istanbul, 34096, Turkey. gulfidan70@gmail.com.
Fatma Ates AlkanDepartment of Biophysics, Istanbul University Cerrahpasa Medical Faculty, Fatih, Istanbul, 34098, Turkey.
Kazim KorkmazDepartment of Cardiology Disease, Haseki Training and Research Hospital, Millet St Fatih, Istanbul, 34096, Turkey.
Zuhal Aydan SaglamDepartment of Family Practitioners, Haseki Training and Research Hospital, Millet St Fatih, Istanbul, 34096, Turkey.
Denizhan KarisDepartment of Biophysics, Istanbul University Cerrahpasa Medical Faculty, Fatih, Istanbul, 34098, Turkey.
Mustafa YenigunDepartment of Internal Disease, Haseki Training and Research Hospital, Millet St Fatih, Istanbul, 34096, Turkey.
Meltem ErcanDepartment of Biophysics, Istanbul University Cerrahpasa Medical Faculty, Fatih, Istanbul, 34098, Turkey.
Haseki Eğitim ve Araştırma Hastanesi · TRIstanbul University · TRIstanbul University-Cerrahpaşa · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of smoking on blood viscosity is widely known. There are, however, few studies on the effect of blood viscosity on pulmonary circulation.

methodsWe aimed to observe the relationship between blood viscosity and pulmonary circulation among smokers and non-smokers. The study comprised 114 subjects in three groups: group 1, ex-smokers; group 2, smoked at least 10 packs/year and still smoking; group 3, never smoked. Blood viscosity (BV), pulmonary blood flow (PBF), and right ventricular systolic pressure (RVSP) were measured in all subjects.

resultsPBF was significantly lower in group 1 compared with group 3 (p < 0.05). BV in group 1 was significantly higher than group 3 (p < 0.05) while BV in group 2 was significantly higher than group 3 (p < 0.05). PBF in group 2 was significantly lower than group 3 (p = 0.01).

conclusionsWe believe that BV is a significant and forgotten factor that plays an important role in pulmonary and cardiovascular diseases. BV may affect PF even during the course of smoking, and before the clinical onset of chronic obstructive pulmonary disease (COPD). Therefore, individuals at risk of pulmonary hypertension could be detected earlier with a simple blood test.

Identifiers

PMID27234385
PMCPMC6733503
OpenAlexW2117158195

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.