Evidence map›Paper›PMID 27233894›Full record

ReviewBMC infectious diseases2016

Fecal microbiota transplantation for severe clostridium difficile infection after left ventricular assist device implantation: a case control study and concise review on the local and regional therapies.

Zeina Z Berro, Righab H Hamdan, Israa H Dandache, Mohamad N Saab, Hussein H Karnib, Mahmoud H Younes

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Current challenges in the treatment of severeTherapeutic advances in gastroenterology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zeina Z BerroGastroentorology Department, Al Rassoul Al Aazam Hospital, Beirut, Lebanon.
Righab H HamdanCardiology Department, Beirut Cardiac Institute, Beirut, Lebanon.
Israa H DandacheMedical Research Center, Al Rassoul Al Aazam Hospital, Beirut, Lebanon.
Mohamad N SaabCardiothoracic Surgery Department, Beirut Cardiac Institute, Beirut, Lebanon.
Hussein H KarnibMedical Research Center, Al Rassoul Al Aazam Hospital, Beirut, Lebanon.
Mahmoud H YounesMedical Research Center, Al Rassoul Al Aazam Hospital, Beirut, Lebanon. myouness55@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe report herein a case of fecal microbiota transplantation (FMT) used for severe Clostridium difficile infection for a 65-year-old Lebanese man who underwent left ventricular assist device implantation. To the best of our knowledge this is the first case report from Lebanon and the region presenting such technique. CASE PRESENTATION: The patient experienced diarrhea and rectal bleeding and was diagnosed of pseudomembranous colitis (PMC). His condition failed to improve on maximal pharmacological therapy. Protocolectomy, an invasive operation consisting in resection of the entire colon and rectum seemed to be the last resort before the patient responded to FMT given through gastroscopy.

conclusionDespite the increasing experience with FMT for C. difficile infection, published evidence in severe related cases from this region is very limited. Hence, we promote adjunctive FMT, an effective noninvasive method, to be considered as a promising early treatment option in severe C. difficile infection.

Indexed as

Clostridioides difficileFecal Microbiota TransplantationAgedCase-Control StudiesClostridium InfectionsDiarrheaEnterocolitis, PseudomembranousFecesGastrointestinal HemorrhageHeart-Assist DevicesHumansLebanonMaleProsthesis ImplantationProsthesis-Related InfectionsFecal microbiota transplantation3Left ventricular assist device implantation2Pseudomembranous colitis4Severe Clostridium difficile1Therapy5

Identifiers

PMID27233894
PMCPMC4884352

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.