Evidence map›Paper›PMID 27233780›Full record

ReviewWorld journal of urology2017

Update of the ICUD-SIU consultation on upper tract urothelial carcinoma 2016: treatment of low-risk upper tract urothelial carcinoma.

Rao S Mandalapu, Mesut Remzi, Theo M de Reijke, Vitaly Margulis, J Palou, A Kapoor, Ofer Yossepowitch, Jonathan Coleman, Olivier Traxer, J Kyle Anderson and 5 more

Abstract readReview
In one paragraph

Review in World journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Head-to-head comparisons ofInternational urology and nephrology · 2023
    Article
  7. Single-use flexible ureteroscopes: ComparativeAsian journal of urology · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Risk stratification for upper tract urinary carcinoma.Translational andrology and urology · 2020
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Enhanced Endoscopy in Bladder Cancer.Current urology reports · 2018
    Review
  18. Reflections on personalized management of UTUC.World journal of urology · 2018
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Rao S Mandalapu, Houston, TX, USA.
Mesut RemziLKH Korneuburg, Korneuburg, Austria.
Theo M de ReijkeAMC University Hospital, Amsterdam, The Netherlands.
Vitaly MargulisDepartment of Urology, University of Texas Southwestern, Dallas, TX, USA.
J PalouFundacio Puigvert, Barcelona, Spain.
A KapoorMcMaster University, Hamilton, ON, Canada.
Ofer YossepowitchRabin Medical Center, Tel Aviv University, Tel Aviv, Israel.
Jonathan ColemanDepartment of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Olivier TraxerHôpital Tenon, Université Pierre et Marie Curie Paris 6, Paris, France.
J Kyle AndersonUniversity of Minnesota Medical Center, Minneapolis, MN, USA.
James CattoAcademic Urology Unit, University of Sheffield, Sheffield, UK.
Jean de la RosetteAMC University Hospital, Amsterdam, The Netherlands.
Timothy O'BrienGuy's and St. Thomas' NHS Foundation Trust, London, UK.
Anthony ZlottaMt. Sinai Hospital, Toronto, ON, Canada.
Surena F MatinDepartment of Urology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1373, Houston, TX, 77030, USA. surmatin@mdanderson.org.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Kathrin Milbury · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

introductionThe conservative management of upper tract urothelial carcinoma (UTUC) has historically been offered to patients with imperative indications. The recent International Consultation on Urologic Diseases (ICUD) publication on UTUC stratified treatment allocations based on high- and low-risk groups. This report updates the conservative management of the low-risk group.

methodsThe ICUD for low-risk UTUC working group performed a thorough review of the literature with an assessment of the level of evidence and grade of recommendation for a variety of published studies in this disease space. We update these publications and provide a summary of that original report.

resultsThere are no prospective randomized controlled studies to support surgical management guidelines. A risk-stratified approach based on clinical, endoscopic, and biopsy assessment allows selection of patients who could benefit from kidney-preserving procedures with oncological outcomes potentially similar to radical nephroureterectomy with bladder cuff excision, with the added benefit of renal function preservation. These treatments are aided by the development of high-definition flexible digital URS, multi-biopsies with the aid of access sheaths and other tools, and promising developments in the use of adjuvant topical therapy.

conclusionsRecent developments in imaging, minimally invasive techniques, multimodality approaches, and adjuvant topical regimens and bladder cancer prevention raise the hope for improved risk stratification and may greatly improve the endoscopic treatment for low-risk UTUC.

Indexed as

Administration, IntravesicalAdministration, TopicalAntineoplastic AgentsCarcinoma in SituCarcinoma, Transitional CellCombined Modality TherapyCystoscopyDisease-Free SurvivalHumansKidney NeoplasmsKidney PelvisLymph Node ExcisionMinimally Invasive Surgical ProceduresNephrectomyNephrostomy, PercutaneousOrgan Sparing TreatmentsAntineoplastic AgentsCalycesNephroureterectomyRenal pelvisUpper tractUreteroscopyUrothelial cancer

Identifiers

PMID27233780
PMCPMC5554604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.