Evidence map›Paper›PMID 27233680›Full record

ArticleJournal of the American Dental Association (1939)2016

Transmission of blood-borne pathogens in US dental health care settings: 2016 update.

Jennifer L Cleveland, Shellie Kolavic Gray, Jennifer A Harte, Valerie A Robison, Anne C Moorman, Barbara F Gooch

3 registry-linked trialsAbstract read
In one paragraph

Article in Journal of the American Dental Association (1939), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04584684 phase2terminatednot on this mapstarted 2020, after this paper: background citation

Antiviral Efficacy and Acceptability of Therapeutic Antiseptic Mouth Rinses for Inactivation of COVID SARS-2 Virus

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2020 to 2021Enrolled128ConditionsCovid19, Coronavirus Infection, SARS-CoV-2 InfectionArms0.9% w/v NaCL Saline, 1.5% w/v Hydrogen Peroxide, 0.12% Chlorohexidine Gluconate, 27% Ethanol plus essential oils, 0.5% w/v Povidone-iodide
NCT04748783 phase2terminatednot on this mapstarted 2021, after this paper: background citation

Antiviral Efficacy and Acceptability of Therapeutic Antiseptic Mouth Rinses for Inactivation of COVID SARS-2 Virus

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2021 to 2021Enrolled2ConditionsCOVID19, Coronavirus Infection, SARS CoV-2 InfectionArmsWater, Peroxyl, Periogard, Colgate Total Zero
NCT05178173 nacompletednot on this mapstarted 2022, after this paper: background citation

Antiviral Efficacy of Oral Rinses for Inactivation of COVID-19 (MOR2)

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2022 to 2023Enrolled230ConditionsCOVID-19, Coronavirus Infection, SARS CoV 2 InfectionArmsPlacebo Comparator: Sterile Water, 27% Ethanol plus essential oils, 0.075% Cetylpyridinium Chloride
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer L Cleveland
Shellie Kolavic Gray
Jennifer A Harte
Valerie A Robison
Anne C Moorman
Barbara F Gooch

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundDuring the past decade, investigators have reported transmissions of blood-borne pathogens (BBPs) in dental settings. In this article, the authors describe these transmissions and examine the lapses in infection prevention on the basis of available information.

methodsThe authors reviewed the literature from 2003 through 2015 to identify reports of the transmission of BBPs in dental settings and related lapses in infection prevention efforts, as well as to identify reports of known or suspected health care-associated BBP infections submitted by state health departments to the Centers for Disease Control and Prevention.

resultsThe authors identified 3 published reports whose investigators described the transmission of hepatitis B virus and hepatitis C virus. In 2 of these reports, the investigators described single-transmission events (from 1 patient to another) in outpatient oral surgery practices. The authors of the third report described the possible transmission of hepatitis B virus to 3 patients and 2 dental health care personnel in a large temporary dental clinic. The authors identified lapses in infection prevention practices that occurred during 2 of the investigations; however, the investigators were not always able to link a specific lapse to a transmission event. Examples of lapses included the failure to heat-sterilize handpieces between patients, a lack of training for volunteers on BBPs, and the use of a combination of unsafe injection practices.

conclusionsThe authors found that reports describing the transmission of BBPs in dental settings since 2003 were rare. Failure to adhere to Centers for Disease Control and Prevention recommendations for infection control in dental settings likely led to disease transmission in these cases. PRACTICAL IMPLICATIONS: The existence of these reports emphasizes the need to improve dental health care personnel's understanding of the basic principles and implementation of standard precautions through the use of checklists, policies, and practices.

Indexed as

Blood-Borne PathogensCross InfectionDental CareEquipment ContaminationHepatitis BHepatitis CHumansOral Surgical ProceduresSterilizationUnited Statesblood-borne pathogensdentistryhealth care–associated infectionhepatitis B virushepatitis C virushuman immunodeficiency virusInfection controlinfection preventionstandard precautions

Identifiers

PMID27233680
PMCPMC5084444

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.