ArticlePhysiological reports2016
Comparison of noninvasive pulse transit time estimates as markers of blood pressure using invasive pulse transit time measurements as a reference.
Article in Physiological reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Cuffless Devices for the Measurement of Blood Pressure: A Scientific Statement From the American Heart Association.Hypertension (Dallas, Tex. : 1979) · 2026Review
- Pulse Wave Velocity: Methodology, Clinical Applications, and Interplay with Heart Rate Variability.Reviews in cardiovascular medicine · 2024Review
- Investigating the relationship between early cardiovascular disease markers and loneliness in young adults.Scientific reports · 2024Article
- Practical Application of a New Cuffless Blood Pressure Measurement Method.Pathophysiology : the official journal of the International Society for Pathophysiology · 2023Article
- Smartphone-Based Blood Pressure Monitoring via the Oscillometric Finger Pressing Method: Analysis of Oscillation Width Variations Can Improve Diastolic Pressure Computation.IEEE transactions on bio-medical engineering · 2023Article
- Intraoperative Beat-to-Beat Pulse Transit Time (PTT) Monitoring via Non-Invasive Piezoelectric/Piezocapacitive Peripheral Sensors Can Predict Changes in Invasively Acquired Blood Pressure in High-Risk Surgical Patients.Sensors (Basel, Switzerland) · 2023Article
- The Microsoft Research Aurora Project: Important Findings on Cuffless Blood Pressure Measurement.Hypertension (Dallas, Tex. : 1979) · 2023Review
- Advancement in the Cuffless and Noninvasive Measurement of Blood Pressure: A Review of the Literature and Open Challenges.Bioengineering (Basel, Switzerland) · 2022Review
- Estimation of systolic blood pressure by Random Forest using heart sounds and a ballistocardiogram.Scientific reports · 2022Article
- Wearable Cuff-Less Blood Pressure Estimation at Home via Pulse Transit Time.IEEE journal of biomedical and health informatics · 2021Article
- Cuffless Blood Pressure Measurement Using a Smartphone-Case Based ECG Monitor with Photoplethysmography in Hypertensive Patients.Sensors (Basel, Switzerland) · 2021Article
- Comprehensive pregnancy monitoring with a network of wireless, soft, and flexible sensors in high- and low-resource health settings.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- A novel art of continuous noninvasive blood pressure measurement.Nature communications · 2021Article
- Multivariate Correlation Measures Reveal Structure and Strength of Brain-Body Physiological Networks at Rest and During Mental Stress.Frontiers in neuroscience · 2020Article
- Multimodal Monitoring of Cardiovascular Responses to Postural Changes.Frontiers in physiology · 2020Article
- Pulse transit time estimation of aortic pulse wave velocity and blood pressure using machine learning and simulated training data.PLoS computational biology · 2019Article
- Multimodal Wrist Biosensor for Wearable Cuff-less Blood Pressure Monitoring System.Scientific reports · 2019Article
- Continuous Blood Pressure Monitoring as a Basis for Ambient Assisted Living (AAL) - Review of Methodologies and Devices.Journal of medical systems · 2019Review
- Current Status and Prospects of Health-Related Sensing Technology in Wearable Devices.Journal of healthcare engineering · 2019Review
- Cuff-Less Methods for Blood Pressure Telemonitoring.Frontiers in cardiovascular medicine · 2019Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Pulse transit time (PTT) measured as the time delay between invasive proximal and distal blood pressure (BP) or flow waveforms (invasive PTT [I-PTT]) tightly correlates with BP PTT estimated as the time delay between noninvasive proximal and distal arterial waveforms could therefore permit cuff-less BP monitoring. A popular noninvasive PTT estimate for this application is the time delay between ECG and photoplethysmography (PPG) waveforms (pulse arrival time [PAT]). Another estimate is the time delay between proximal and distal PPG waveforms (PPG-PTT). PAT and PPG-PTT were assessed as markers of BP over a wide physiologic range using I-PTT as a reference. Waveforms for determining I-PTT, PAT, and PPG-PTT through central arteries were measured from swine during baseline conditions and infusions of various hemodynamic drugs. Diastolic, mean, and systolic BP varied widely in each subject (group average (mean ± SE) standard deviation between 25 ± 2 and 36 ± 2 mmHg). I-PTT correlated well with all BP levels (group average R(2) values between 0.86 ± 0.03 and 0.91 ± 0.03). PPG-PTT also correlated well with all BP levels (group average R(2) values between 0.81 ± 0.03 and 0.85 ± 0.02), and its R(2) values were not significantly different from those of I-PTT PAT correlated best with systolic BP (group average R(2) value of 0.70 ± 0.04), but its R(2) values for all BP levels were significantly lower than those of I-PTT (P < 0.005) and PPG-PTT (P < 0.02). The pre-ejection period component of PAT was responsible for its inferior correlation with BP In sum, PPG-PTT was not different from I-PTT and superior to the popular PAT as a marker of BP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.