ArticleLangenbeck's archives of surgery2016
Subtotal parathyroidectomy for secondary renal hyperparathyroidism: a 20-year surgical outcome study.
Article in Langenbeck's archives of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Renal hyperparathyroidism: comparative outcomes of parathyroidectomy in two regional centres over 14 years.Annals of the Royal College of Surgeons of England · 2026Article
- Article
- Hungry bone syndrome in peritoneal dialysis patients after parathyroid surgery.Endocrine connections · 2023Article
- Forestalling Hungry Bone Syndrome after Parathyroidectomy in Patients with Primary and Renal Hyperparathyroidism.Diagnostics (Basel, Switzerland) · 2023Review
- Investigating the effectiveness of intraoperative rapid parathyroid hormone assay in parathyroidectomy surgery in patients with secondary hyperparathyroidism.BMC endocrine disorders · 2023Article
- Article
- Intraoperative Parathyroid Hormone Monitoring-Guided Subtotal Parathyroidectomy is an Effective and Valid Surgical Procedure for Secondary Hyperparathyroidism.Sisli Etfal Hastanesi tip bulteni · 2023Article
- Autotransplantation of parathyroid tissue into subcutaneous subclavicular area following total parathyroidectomy in secondary hyperparathyroidism.Journal of endocrinological investigation · 2022Article
- Article
- Type of subtotal parathyroidectomy and evolution of parathyroid hormone levels in end-stage renal disease patients: a retrospective cohort study.International urology and nephrology · 2020Article
- Surgical Outcomes of Subtotal Parathyroidectomy for Renal Hyperparathyroidism.Clinical and experimental otorhinolaryngology · 2020Article
- Therapeutic efficacy of two surgical methods on the secondary hyperparathyroidism.Gland surgery · 2020Article
- Postsurgical Evaluation of Secondary Nephrogenic Hyperparathyroidism.Current medical science · 2019Article
- Novel insights into parathyroid hormone: report of The Parathyroid Day in Chronic Kidney Disease.Clinical kidney journal · 2019Article
- Safety and efficacy of subtotal or total parathyroidectomy for patients with secondary or tertiary hyperparathyroidism in four academic centers in the Netherlands.Langenbeck's archives of surgery · 2018Article
- Therapeutic experience of severe and recurrent secondary hyperparathyroidism in a patient on hemodialysis for 18 years: A case report.Medicine · 2018Article
- Total Parathyroidectomy with Subcutaneous Parathyroid Forearm Autotransplantation in the Treatment of Secondary Hyperparathyroidism: A Single-Center Experience.International journal of endocrinology · 2018Article
- Article
- Near total parathyroidectomy for the treatment of renal hyperparathyroidism.Gland surgery · 2017Article
- Secondary Hyperparthyroidism: Pathogenesis, Diagnosis, Preventive and Therapeutic Strategies.Reviews in endocrine & metabolic disorders · 2017Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to evaluate the outcomes of surgery for patients with secondary renal hyperparathyroidism (rHPT).
methodsThis is a retrospective cohort study. Our institutional database was searched for eligible patients treated in 1995-2014. The inclusion criterion was initial parathyroidectomy for rHPT. Clinical and follow-up data were analyzed to estimate the cure rate (primary outcome), and morbidity (secondary outcome).
resultsThe study group comprised 297 patients (154 females, age 44.5 ± 13.7 years, follow-up 24.6 ± 10.5 months), including 268 (90.2 %) patients who had underwent subtotal parathyroidectomy, and 29 (9.8 %) who had had incomplete parathyroidectomy. Intraoperative iPTH assay was utilized in 207 (69.7 %) explorations. Persistent rHPT occurred in 12/268 (4.5 %) patients after subtotal parathyroidectomy and 5/29 (17.2 %) subjects after incomplete parathyroidectomy (p = 0.005). The patients operated on with intraoperative iPTH assay had a higher cure rate than non-monitored individuals, 201/207 (97.1 %) vs. 79/90 (87.8 %), respectively (p = 0.001). In-hospital mortality occurred in 1/297 (0.3 %) patient. The hungry bone syndrome occurred in 84/268 (31.3 %) patients after subtotal parathyroidectomy and 2/29 (6.9 %) subjects after incomplete parathyroidectomy (p = 0.006). Transient recurrent laryngeal nerve paresis occurred in 14/594 (2.4 %) and permanent in 5/594 (0.8 %) nerves at risk.
conclusionsSubtotal parathyroidectomy is a safe and efficacious treatment for patients with rHPT. Utilization of intraoperative iPTH assay can guide surgical exploration and improve the cure rate.
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