ArticleRestorative neurology and neuroscience2016
Cerebellar tDCS as a novel treatment for aphasia? Evidence from behavioral and resting-state functional connectivity data in healthy adults.
Article in Restorative neurology and neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Probing the linguistic cerebellum: a qualitative review of the effects of cerebellar neurostimulation on language processing.Frontiers in psychiatry · 2026Pooled it
- Non-invasive brain stimulation for the improvement of lower extremity motor function in patients with stroke: a systematic review and network meta-analysis.Frontiers in neurology · 2025Pooled it
- Cerebellar transcranial direct current stimulation improves quality of life in individuals with chronic poststroke aphasia.Scientific reports · 2025Trial
- Electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval.Brain structure & function · 2023Trial
- White matter predictors of cerebellar tDCS treatment effects in aphasia rehabilitation.Frontiers in neurologyTrial
- Pre-frontal tDCS improves sustained attention and promotes artificial grammar learning in aphasia: An open-label study.Brain stimulationTrial
- The cerebellum specializes for language even in the absence of contralateral neocortical inputs.bioRxiv : the preprint server for biology · 2026Article
- Language network disruption in patients with Lewy body diseases.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Exploring the Effects of a Computerized Naming Intervention Combined with Cerebellar tDCS in Cantonese-Speaking Individuals with Aphasia.Brain sciences · 2026Article
- Cerebellar tDCS Modulates Corticocortical Functional Networks in a Regionally Specific Manner.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- Cerebello-Cerebral Resting-State Functional Connectivity in Poststroke Aphasia.Brain connectivity · 2025Article
- Time Dependent Effects of Cerebellar tDCS on Cerebello-cortical Connectivity Networks in Young Adults.Cerebellum (London, England) · 2025Article
- Efficacy of cerebellar cathodal transcranial direct current stimulation for post-stroke aphasia: A randomized controlled trial.Clinical neurophysiology practice · 2025Article
- Effects of Cerebellar Non-Invasive Stimulation on Neurorehabilitation in Stroke Patients: An Updated Systematic Review.Biomedicines · 2024Review
- Cerebellar compensation: a case of aphasia due to cerebellar hemorrhage.Journal of neurology · 2024Article
- Protocol for Cerebellar Stimulation for Aphasia Rehabilitation (CeSAR): A randomized, double-blind, sham-controlled trial.PloS one · 2024Article
- Article
- Effects of Cerebellar Transcranial Direct Current Stimulation in Bilingual Logopenic Primary Progressive Aphasia.Journal of Alzheimer's disease reports · 2024Article
- Cerebellar Neuromodulation Impacts Reading Fluency in Young Adults.Neurobiology of language (Cambridge, Mass.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundAphasia is an acquired deficit in the ability to communicate through language. Noninvasive neuromodulation offers the potential to boost neural function and recovery, yet the optimal site of neuromodulation for aphasia has yet to be established. The right posterolateral cerebellum is involved in multiple language functions, interconnects with left-hemisphere language cortices, and is crucial for optimization of function and skill acquisition, suggesting that cerebellar neuromodulation could enhance aphasia rehabilitation.
objectiveTo provide preliminary behavioral and functional connectivity evidence from healthy participants that cerebellar neuromodulation may be useful for rehabilitation of aphasia.
methodsIn Experiment 1, 76 healthy adults performed articulation and verbal fluency tasks before and after anodal, cathodal or sham transcranial direct current stimulation (tDCS) was applied over two cerebellar locations (anterior, right posterolateral). In Experiment 2, we examined whether anodal tDCS over the right posterolateral cerebellum modulated resting-state functional connectivity in language networks in 27 healthy adults.
resultsTDCS over the right posterolateral cerebellum significantly improved phonemic fluency. Cerebellar neuromodulation increased functional connectivity between the cerebellum and areas involved in the motor control of speech, and enhanced the correlations between left-hemisphere language and speech-motor regions.
conclusionWe provide proof-of-principle evidence that cerebellar neuromodulation improves verbal fluency and impacts resting-state connectivity in language circuits. These findings suggest that the cerebellum is a viable candidate for neuromodulation in people with aphasia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.