Evidence map›Paper›PMID 27232888›Full record

ArticleJournal of medical virology2016

Rhinovirus species and clinical characteristics in the first wheezing episode in children.

Riitta Turunen, Tuomas Jartti, Yury A Bochkov, James E Gern, Tytti Vuorinen

Open access · greenAbstract read
In one paragraph

Article in Journal of medical virology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 32 citations in OpenAlex.

  1. Duration and severity of asthma-like episodes in young children vary by viral and bacterial triggers.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection.American journal of respiratory and critical care medicine · 2021
    Article
  12. Article
  13. Review
  14. Review
  15. Observational
  16. Review
  17. Rhinovirus C15 Induces Airway Hyperresponsiveness via Calcium Mobilization in Airway Smooth Muscle.American journal of respiratory cell and molecular biology · 2020
    Article
  18. Role of viruses in asthma.Seminars in immunopathology · 2020
    Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Riitta TurunenDepartment of Pediatrics, Turku University Hospital, Turku, Finland. riitta.turunen@utu.fi.
Tuomas JarttiDepartment of Pediatrics, Turku University Hospital, Turku, Finland.
Yury A BochkovDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
James E GernDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Tytti VuorinenDepartment of Virology, University of Turku, Finland.
University of Turku · FIUniversity of Wisconsin–Madison · USTurku University Hospital · FI

Funding

Virus-Bacterial Interactions and Exacerba of AsthmaP01HL070831 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BOCHKOV, YURY A · 2002 to 2017
$31.3M
Wisconsin Infant Study Cohort (WISC)U19AI104317 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern, CHRISTINE Marie SEROOGY · 2013 to 2026
$22.5M
NHLBI NIH HHS P01 HL070831NIAID NIH HHS U19 AI104317
6 · The paper itself

Abstract

The clinical data on the first wheezing episodes induced by different rhinovirus (RV) species are still limited. We aimed to investigate the prevalence of RV genotypes, sensitization status, and clinical characteristics of patients having a respiratory infection caused by either different RV species or other respiratory viruses. The study enrolled 111 patients (aged 3-23 months, 79% hospitalized, 76% with RV infection) with the first wheezing episode. RV-specific sequences were identified by partial sequencing of VP4/VP2 and 5' non-coding regions with 80% success rate. The investigated clinical and laboratory variables included atopic characteristics and illness severity, parental atopic illnesses, and parental smoking. Of the study children, 56% percent had >1 atopic characteristic (atopy, eczema and/or blood eosinophil count >0.4 × 10

Indexed as

FemaleFinlandGenotypeHumansInfantMalePicornaviridae InfectionsPolymerase Chain ReactionPrevalenceRespiratory SoundsRespiratory Tract InfectionsRhinovirusSequence Analysis, DNASeverity of Illness IndexViral ProteinsViral Proteinsatopychildrengenotypesrhinovirussequencingwheezing

Identifiers

PMID27232888
PMCPMC5140033
OpenAlexW2407250752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.