Evidence map›Paper›PMID 27232381›Full record

ReviewCurrent opinion in microbiology2016

The diversity of insect antiviral immunity: insights from viruses.

João T Marques, Jean-Luc Imler

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 108 citations in OpenAlex.

  1. Article
  2. Article
  3. RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Review
  5. The diversity of viral community inFrontiers in microbiology · 2025
    Article
  6. Proteomics analysis of soluble secreted proteins ofFrontiers in cellular and infection microbiology · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Insects · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Insects · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

João T MarquesDepartment of Biochemistry and Immunology, Universidade Federal de Minas Gerais, Belo Horizonte, CEP 31270-901, Brazil; CNRS UPR9022, IBMC, Strasbourg, France. Electronic address: jtm@ufmg.br.
Jean-Luc ImlerCNRS UPR9022, IBMC, Strasbourg, France; Faculté des Sciences de la Vie, Université de Strasbourg, Strasbourg, France. Electronic address: jl.imler@unistra.fr.
Centre National de la Recherche Scientifique · FRUniversidade Federal de Minas Gerais · BR

Funding

Sequencing CoreP01AI070167 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI BEUTLER, BRUCE A · 2006 to 2016
$27.2M
NIAID NIH HHS P01 AI070167
6 · The paper itself

Abstract

Insects represent over 70% of all animal species. Recent virome analyses reveal unprecedented genetic diversity of insect viruses, which appears to match that of their hosts. Thus, insect-virus interactions may provide information on a vast repertoire of antiviral immune mechanisms. Tapping into this diversity is challenging because of several constraints imposed by the uniqueness of each insect model. Nevertheless, it is clear that many conserved and divergent pathways participate in the control of viral infection in insects. Co-evolution between hosts and viruses favors the development of immune evasion mechanisms by the pathogen. Viral suppressors can offer unique perspective on host pathways and emphasize the importance of RNA interference, apoptosis, but also NF-κB pathways and translation control in insect antiviral immunity.

Indexed as

AnimalsDicistroviridaeDrosophilaHemocytesHost-Pathogen InteractionsImmune EvasionImmunity, Innate

Identifiers

PMID27232381
PMCPMC4983534
OpenAlexW2407769349

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.