ReviewOcular immunology and inflammation2016
Review for Disease of the Year: Epidemiology of HLA-B27 Associated Ocular Disorders.
Review in Ocular immunology and inflammation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A large meta-analysis identifies genes associated with anterior uveitis.Nature communications · 2023Pooled it
- Exploring the Involvement ofLife (Basel, Switzerland) · 2026Review
- Dermatological Indicators of Systemic Autoimmune Disease: Clinical Links to Ocular Involvement.Dermatology practical & conceptual · 2026Review
- Impact of complications in adult anterior uveitis in a Finnish single-centre registry study.BMJ open ophthalmology · 2025Article
- Long COVID and the development of new-onset uveitis: a large database study.Journal of ophthalmic inflammation and infection · 2025Article
- High resolution class I HLA-A, -B, and -C diversity in Eastern and Southern African populations.Scientific reports · 2025Article
- Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.Frontiers in immunology · 2025Article
- The management of adult and paediatric uveitis for rheumatologists.Nature reviews. Rheumatology · 2024Review
- Sequence of Events in the Pathogenesis of Axial Spondyloarthritis: A Current Review-2023 SPARTAN Meeting Proceedings.Current rheumatology reports · 2024Review
- Rheumatic diseases detected in patients presenting with uveitis.Northern clinics of Istanbul · 2024Article
- Orbital Doppler ultrasonography evaluation in patients with ankylosing spondylitis: A prospective study.Northern clinics of Istanbul · 2024Article
- Long term complications and vision loss in HLA-B27 uveitis.Eye (London, England) · 2023Article
- A Prospective Study of Clinical Features of Anterior Uveitis in Taiwan.Journal of ophthalmology · 2023Article
- Differentiating nonradiographic axial spondyloarthritis from its mimics: a narrative review.BMC musculoskeletal disorders · 2022Review
- Article
- Uveitis as an Open Window to Systemic Inflammatory Diseases.Journal of clinical medicine · 2021Article
- Predictive Metagenomic Analysis of Autoimmune Disease Identifies Robust Autoimmunity and Disease Specific Microbial Signatures.Frontiers in microbiology · 2021Article
- Immunological tests and their interpretation in uveitis.Indian journal of ophthalmology · 2020Review
- A case of severe flare reaction observed in HLA B27 associated acute anterior uveitis.BMC ophthalmology · 2020Article
- Recent Developments in HLA B27 Anterior Uveitis.Frontiers in immunology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Acute anterior uveitis is generally recognized as the most common form of uveitis. An association with HLA-B27 is seen in approximately half of cases of acute anterior uveitis. The prevalence of HLA-B27 varies widely between ethnic populations, with an approximate 8-10% prevalence in non-Hispanic whites and lower prevalence in Mexican- (4%) and African- (2-4%) Americans. A group of systemic inflammatory diseases, the spondyloarthropathies, similarly demonstrates a strong association with HLA-B27. The strength of association varies, depending on the specific spondyloarthropathy, with the strongest association found in patients with ankylosing spondylitis. The majority of patients with HLA-B27 associated uveitis will have an underlying spondyloarthropathy. Suspicion for HLA-B27 associated uveitis should prompt a careful clinical history to assess for features of a spondyloarthropathy as the characteristics of any associated uveitis may vary.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.