Evidence map›Paper›PMID 27231903›Full record

ReviewInternational journal of molecular sciences2016

Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics.

Manoj Ghaste, Robert Mistrik, Vladimir Shulaev

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
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  8. Review
  9. Article
  10. Advances in Mass Spectrometry-Metabolomics Based Approaches.Advances in experimental medicine and biology · 2023
    Article
  11. Article
  12. Article
  13. Multi-Omics Strategies for Investigating the Microbiome in Toxicology Research.Toxicological sciences : an official journal of the Society of Toxicology · 2022
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Manoj GhasteDepartment of Biological Sciences, College of Arts and Sciences, University of North Texas, Denton, TX 76203, USA. manoj.ghaste@unt.edu.
Robert MistrikHighChem, Bratislava 81104, Slovakia. robert.mistrik@highchem.com.
Vladimir ShulaevDepartment of Biological Sciences, College of Arts and Sciences, University of North Texas, Denton, TX 76203, USA. shulaev@unt.edu.

Funding

Optimized Combination Antimalarial Drug TherapyR01AI111962 · NIAID · GEORGETOWN UNIVERSITY · PI ROEPE, PAUL D., SULLIVAN, DAVID JOSEPH · 2014 to 2018
$4.9M
NIAID NIH HHS R01 AI111962
6 · The paper itself

Abstract

Metabolomics, along with other "omics" approaches, is rapidly becoming one of the major approaches aimed at understanding the organization and dynamics of metabolic networks. Mass spectrometry is often a technique of choice for metabolomics studies due to its high sensitivity, reproducibility and wide dynamic range. High resolution mass spectrometry (HRMS) is a widely practiced technique in analytical and bioanalytical sciences. It offers exceptionally high resolution and the highest degree of structural confirmation. Many metabolomics studies have been conducted using HRMS over the past decade. In this review, we will explore the latest developments in Fourier transform mass spectrometry (FTMS) and Orbitrap based metabolomics technology, its advantages and drawbacks for using in metabolomics and lipidomics studies, and development of novel approaches for processing HRMS data.

Indexed as

Lipid MetabolismCyclotronsFourier AnalysisMass SpectrometryMetabolomicsFT-ICR-MSFTMShigh resolution mass spectrometrylipidomicsmetabolomicsmetabolomics data analysisOrbitrap-MS

Identifiers

PMID27231903
PMCPMC4926350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.