ArticleBiochemistry and biophysics reports2016
High salt induces anti-inflammatory MΦ2-like phenotype in peripheral macrophages.
Article in Biochemistry and biophysics reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Sodium accumulation in breast cancer predicts malignancy and treatment response.British journal of cancer · 2022Trial
- Trained immunity induced by high-salt diet impedes stroke recovery.EMBO reports · 2023Article
- Acid Dentin Lysate Modulates Macrophage Polarization and Osteoclastogenesis In Vitro.Materials (Basel, Switzerland) · 2021Article
- Cancer Salt Nostalgia.Cells · 2021Article
- Review
- Lactate Alters Metabolism in Human Macrophages and Improves Their Ability to KillFrontiers in immunology · 2021Article
- Interferon-Gamma Stimulated Murine MacrophagesBioelectricity · 2020Article
- Sodium homeostasis in the tumour microenvironment.Biochimica et biophysica acta. Reviews on cancer · 2019Review
- Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: A Comparative Study.Mediators of inflammation · 2019Article
- Inflammatory role of high salt level in tumor microenvironment (Review).International journal of oncology · 2017Review
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Macrophages play a critical role in inflammation and antigen-presentation. Abnormal macrophage function has been attributed in autoimmune diseases and cancer progression. Recent evidence suggests that high salt tissue micro-environment causes changes in macrophage activation. In our current report, we studied the role of extracellular sodium chloride on phenotype changes in peripheral circulating monocyte/macrophages collected from healthy donors. High salt (0.2 M NaCl vs basal 0.1 M NaCl) treatment resulted in a decrease in MΦ1 macrophage phenotype (CD11b
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Registered trials
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