Evidence map›Paper›PMID 27231642›Full record

ArticleBiomedical optics express2016

Development of perturbation Monte Carlo methods for polarized light transport in a discrete particle scattering model.

Jennifer Nguyen, Carole K Hayakawa, Judith R Mourant, Vasan Venugopalan, Jerome Spanier

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer NguyenDepartment of Biomedical Engineering, 3120 Natural Sciences II, University of California, Irvine, CA 92697-2715, USA; Laser Microbeam and Medical Program, Beckman Laser Institute, University of California, Irvine Irvine, California 92697, USA.
Carole K HayakawaLaser Microbeam and Medical Program, Beckman Laser Institute, University of California, Irvine Irvine, California 92697, USA; Department of Chemical Engineering and Materials Science, 916 Engineering Tower, University of California, Irvine, CA 92697-2575, USA.
Judith R MourantBioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Vasan VenugopalanDepartment of Biomedical Engineering, 3120 Natural Sciences II, University of California, Irvine, CA 92697-2715, USA; Laser Microbeam and Medical Program, Beckman Laser Institute, University of California, Irvine Irvine, California 92697, USA; Department of Chemical Engineering and Materials Science, 916 Engineering Tower, University of California, Irvine, CA 92697-2575, USA.
Jerome SpanierLaser Microbeam and Medical Program, Beckman Laser Institute, University of California, Irvine Irvine, California 92697, USA.

Funding

LIGHT SCATTERING IN TUMOR AND NORMAL TISSUE MODELSR01CA071898 · NCI · UNIVERSITY OF CALIF-LOS ALAMOS NAT LAB · PI MOURANT, JUDITH R · 1997 to 2012
$7.7M
Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI VENUGOPALAN, VASAN · 2012 to 2017
$7.0M
NCI NIH HHS R01 CA071898NIBIB NIH HHS P41 EB015890
6 · The paper itself

Abstract

We present a polarization-sensitive, transport-rigorous perturbation Monte Carlo (pMC) method to model the impact of optical property changes on reflectance measurements within a discrete particle scattering model. The model consists of three log-normally distributed populations of Mie scatterers that approximate biologically relevant cervical tissue properties. Our method provides reflectance estimates for perturbations across wavelength and/or scattering model parameters. We test our pMC model performance by perturbing across number densities and mean particle radii, and compare pMC reflectance estimates with those obtained from conventional Monte Carlo simulations. These tests allow us to explore different factors that control pMC performance and to evaluate the gains in computational efficiency that our pMC method provides.

Indexed as

(170.0170) Medical optics and biotechnology(170.3660) Light propagation in tissues(170.6510) Spectroscopy, tissue diagnostics(170.6935) Tissue characterization(290.5855) Scattering, polarization

Identifiers

PMID27231642
PMCPMC4871102

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.