Evidence map›Paper›PMID 27231626›Full record

ArticleBiomedical optics express2016

Subcellular chemical and morphological analysis by stimulated Raman scattering microscopy and image analysis techniques.

Annalisa D'Arco, Nadia Brancati, Maria Antonietta Ferrara, Maurizio Indolfi, Maria Frucci, Luigi Sirleto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annalisa D'ArcoNational Research Council (CNR), Institute for Microelectronics and Microsystems, I-80131 Napoli, Italy; Second University of Naples (SUN), Department of Information Engineering, I-81031 Aversa, Italy.
Nadia BrancatiNational Research Council (CNR), Institute for High-Performance Computing and Networking, I-80131 Napoli, Italy.
Maria Antonietta FerraraNational Research Council (CNR), Institute for Microelectronics and Microsystems, I-80131 Napoli, Italy.
Maurizio IndolfiNational Research Council (CNR), Institute for Microelectronics and Microsystems, I-80131 Napoli, Italy.
Maria FrucciNational Research Council (CNR), Institute for High-Performance Computing and Networking, I-80131 Napoli, Italy.
Luigi SirletoNational Research Council (CNR), Institute for Microelectronics and Microsystems, I-80131 Napoli, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The visualization of heterogeneous morphology, segmentation and quantification of image features is a crucial point for nonlinear optics microscopy applications, spanning from imaging of living cells or tissues to biomedical diagnostic. In this paper, a methodology combining stimulated Raman scattering microscopy and image analysis technique is presented. The basic idea is to join the potential of vibrational contrast of stimulated Raman scattering and the strength of imaging analysis technique in order to delineate subcellular morphology with chemical specificity. Validation tests on label free imaging of polystyrene-beads and of adipocyte cells are reported and discussed.

Indexed as

(100.0100) Image processing(170.0110) Imaging systems(180.4315) Nonlinear microscopy(190.5890) Scattering, stimulated(190.7110) Ultrafast nonlinear optics

Identifiers

PMID27231626
PMCPMC4871086

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.