ArticleAmerican sociological review2015
Lifetime Socioeconomic Status, Historical Context, and Genetic Inheritance in Shaping Body Mass in Middle and Late Adulthood.
Article in American sociological review, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 81 citations in OpenAlex.
- Peer influence on obesity: Evidence from a natural experiment of a gene-environment interaction.Social science research · 2021Trial
- Genetic risk for high body mass index before and amidst the obesity epidemic: Cross-cohort analysis of four british birth cohort studies.PLoS genetics · 2026Article
- Life-course socioeconomic status and obesity: scoping review.Population health metrics · 2025Article
- Socioeconomic disadvantage and polygenic risk of overweight in early and mid-life: a longitudinal population cohort study spanning 12 years.The Lancet regional health. Western Pacific · 2024Article
- Exploring the Fetal Origins Hypothesis Using Genetic Data.Social forces; a scientific medium of social study and interpretation · 2024Article
- Factors associated with overweight and obesity among women of reproductive age in Cambodia: Analysis of Cambodia Demographic and Health Survey 2021-22.PLOS global public health · 2024Article
- Challenges in studying the interplay of genes and environment. A study of childhood financial distress moderating genetic predisposition for peak smoking.Journal Of Economic Psychology · 2023Article
- The Future of Social Determinants of Health: Looking Upstream to Structural Drivers.The Milbank quarterly · 2023Article
- Genetic Effect on Body Mass Index and Cardiovascular Disease Across Generations.Circulation. Genomic and precision medicine · 2023Article
- Overweight and obesity among women at reproductive age in Cambodia: Data analysis of Cambodia Demographic and Health Survey 2014.PLOS global public health · 2023Article
- Incarceration, polygenic risk, and depressive symptoms among males in late adulthood.Social science research · 2022Article
- Modeling Interaction and Dispersion Effects in the Analysis of Gene-by-Environment Interaction.Behavior genetics · 2022Article
- Evaluating the Continued Integration of Genetics into Medical Sociology.Journal of health and social behavior · 2021Article
- The impact of late-career job loss and genetic risk on body mass index: Evidence from variance polygenic scores.Scientific reports · 2021Article
- Association of a genetic risk score with BMI along the life-cycle: Evidence from several US cohorts.PloS one · 2020Article
- SES-of-Origin and BMI in Youth: Comparing Germany and Minnesota.Behavior genetics · 2019Article
- Education can reduce health differences related to genetic risk of obesity.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Does education attenuate the genetic risk of obesity? Evidence from U.K. Twins.Economics and human biology · 2018Article
- Father Absence and Accelerated Reproductive Development in Non-Hispanic White Women in the United States.Demography · 2018Article
- Education, Smoking, and Cohort Change: Forwarding a Multidimensional Theory of the Environmental Moderation of Genetic Effects.American sociological review · 2018Article
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Abstract
This study demonstrates body mass in middle and late adulthood as a consequence of the complex interplay among individuals' genes, lifetime socioeconomic experiences, and the historical context in which they live. Drawing on approximately 9,000 genetic samples from the Health and Retirement Study, we first investigate how socioeconomic status (SES) over the life course moderates the impact of 32 established obesity-related genetic variants on body mass index (BMI) in middle and late adulthood. Further, we consider differences across birth cohorts in the genetic influence on BMI and cohort variations in the moderating effects of life-course SES on the genetic influence. Our analyses suggest that persistently low SES over the life course or downward mobility (e.g., high SES in childhood but low SES in adulthood) amplified the genetic influence on BMI, while persistently high SES or upward mobility (e.g., low SES in childhood but high SES in adulthood) compensated for such influence. For more recent birth cohorts, while the genetic influence on BMI became stronger, the moderating effects of lifetime SES on the genetic influence were weaker compared to earlier cohorts. We discuss these findings in light of social changes during the obesity epidemic in the United States.
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