ReviewMicrobial biotechnology2016
Lactobacillus plantarum WCFS1 and its host interaction: a dozen years after the genome.
Review in Microbial biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
66 citing papers in PubMed.
- Comprehensive Genomic Characterization and Probiotic Properties Evaluation of Limosilactobacillus fermentum JAC 231 Isolated from Vaginal Microbiota.Probiotics and antimicrobial proteins · 2026Article
- Genomic and phenotypic insights into the probiotic and antimicrobial potential of Bacillus amyloliquefaciens BCSIR-AJ strain from garlic chutney.Archives of microbiology · 2026Article
- A sustained living coating for infectious keratitis therapy via probiotic consumption and production effects.Science advances · 2026Article
- A Dual-Target Microbial Therapeutic Strategy for Treating Metabolic Diseases: Complementary Mechanisms and Clinical Prospects ofMetabolites · 2026Review
- Global Genomic Landscapes ofLife (Basel, Switzerland) · 2025Article
- Effects of Lactobacillus plantarum on Broiler Health: Integrated Microbial and Metabolomics Analysis.Probiotics and antimicrobial proteins · 2025Article
- Dissecting the High Esterase/Lipase Activity and Probiotic Traits inFoods (Basel, Switzerland) · 2025Article
- A Peek into the Relationship Between Probiotic Characteristics of Lactiplantibacillus plantarum Strains and Sortase A Gene Expression.Current microbiology · 2025Article
- Adaptations of Gram-Negative and Gram-Positive Probiotic Bacteria in Engineered Living Materials.ACS biomaterials science & engineering · 2025Article
- Strategic antagonism: howFrontiers in microbiology · 2025Review
- Evaluation of probiotic properties and complete genome analysis of lactic acid bacteria isolated from crested ibisFrontiers in microbiology · 2025Article
- Genomic Assessment of Potential ProbioticTropical life sciences research · 2024Article
- Characterization of Genomic, Physiological, and Probiotic Features ofFoods (Basel, Switzerland) · 2024Article
- The role ofJournal of oral microbiology · 2024Review
- SynergisticMicrobiome research reports · 2024Review
- Engineered probioticMicrobiology spectrum · 2023Article
- Modulation of the Gut Microbiota by the Plantaricin-ProducingInternational journal of molecular sciences · 2023Article
- Article
- Whole Genome Sequence ofJournal of microbiology and biotechnology · 2023Article
- Antibacterial and Antibiofilm Effects of Lactobacilli Strains against Clinical Isolates ofAntibiotics (Basel, Switzerland) · 2023Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Lactobacillus plantarum WCFS1 is one of the best studied Lactobacilli, notably as its genome was unravelled over 12 years ago. L. plantarum WCFS1 can be grown to high densities, is amenable to genetic transformation and highly robust with a relatively high survival rate during the gastrointestinal passage. In this review, we present and discuss the main insights provided by the functional genomics research on L. plantarum WCFS1 with specific attention for the molecular mechanisms related to its interaction with the human host and its potential to modify the immune system, and induce other health-related benefits. Whereas most insight has been gained in mouse and other model studies, only five human studies have been reported with L. plantarum WCFS1. Hence NCIMB 8826 (the parental strain of L. plantarum WCFS1) in human trials as to capitalize on the wealth of knowledge that is summarized here.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.