Evidence map›Paper›PMID 27231013›Full record

ArticleJournal of fluorescence2016

Synthesis and Photophysical Studies on Naphthalimide Derived Fluorophores as Markers in Drug Delivery.

Nidhi Singh, Ritika Srivastava, Anuradha Singh, Ramendra K Singh

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nidhi SinghBioorganic Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, 211002, India.
Ritika SrivastavaBioorganic Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, 211002, India.
Anuradha SinghBioorganic Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, 211002, India.
Ramendra K SinghBioorganic Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, 211002, India. rksinghsrk@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Derivatives of 4-amino-1,8-naphthalimide containing a free alkyl chain bearing carboxyl group as linker and different substituents at 4-amino function have been synthesized, characterized and studied for their photophysical properties. Steady state fluorescence studies showed quantum yield varied from 0.45 to 0.65 with Stokes shift in the range of 5824-8558 cm(-1). Spectroscopic and physicochemical parameters, like electronic absorption, emission, and extinction coefficient were investigated in order to explore the analytical potential of compounds. Solvatochromic studies demonstrated that all compounds were sensitive towards the polarity of different solvents showing the highest degree of fluorescence in acetonitrile. In addition, the compounds in the presence of ions, viz. Na(+), K(+) and Mg(2+) at concentration of 0.1-2 equivalents, showed a decreasing trend in fluorescence with increasing ionic concentration. TCSPC set - up was used to measure the fluorescence lifetime of compounds, which was found to be bi-exponential with longer and shorter component at their respective amplitudes. The average lifetime of compounds was observed to be 5.76-9.96 ns indicating the possibility of their greater utilization in research and diagnosis.

Indexed as

Drug Delivery Systems1-NaphthylamineChemistry Techniques, SyntheticFluorescent DyesNaphthalimidesQuinolonesSpectrometry, Fluorescence1-Naphthylamine4-amino-1,8-naphthalimideFluorescent DyesNaphthalimidesQuinolonesAmino-naphthalimide derivativeAverage lifetimeQuantum yieldSolvatochromismSteady state fluorescence

Identifiers

PMID27231013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.