Evidence map›Paper›PMID 27230917›Full record

ArticleNeuroradiology2016

Reduced white matter integrity in amateur boxers.

Christian Herweh, Klaus Hess, Uta Meyding-Lamadé, Andreas J Bartsch, Christoph Stippich, Joachim Jost, Birgit Friedmann-Bette, Sabine Heiland, Martin Bendszus, Stefan Hähnel

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In one paragraph

Article in Neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Christian HerwehDepartment of Neuroradiology, University of Heidelberg Medical School, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. christian.herweh@med.uni-heidelberg.de.
Klaus HessDepartment of Neurology, University of Heidelberg Medical School, Heidelberg, Germany.
Uta Meyding-LamadéDepartment of Neurology, Krankenhaus Nordwest, Frankfurt, Germany.
Andreas J BartschDepartment of Neuroradiology, University of Heidelberg Medical School, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Christoph StippichDepartment of Neuroradiology, University Hospital Basel, Basel, Switzerland.
Joachim JostNational Training Center for Boxing, Heidelberg, Germany.
Birgit Friedmann-BetteDepartment of Sports Medicine, University of Heidelberg Medical School, Heidelberg, Germany.
Sabine HeilandDepartment of Neuroradiology, University of Heidelberg Medical School, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Martin BendszusDepartment of Neuroradiology, University of Heidelberg Medical School, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Stefan HähnelDepartment of Neuroradiology, University of Heidelberg Medical School, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DEKrankenhaus Nordwest · DEUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionProfessional boxing can lead to chronic traumatic encephalopathy, a variant of traumatic brain injury (TBI). Its occurrence in amateur boxers is a matter of debate since amateur boxing is considered to be less harmful due to more strict regulations. However, several studies using different methodological approaches have revealed subtle signs of TBI even in amateurs. Diffusion tensor imaging (DTI) is sensitive to microscopic white matter changes and has been proven useful in TBI when routine MR imaging often is unrevealing.

methodsDTI, with tract-based spatial statistics (TBSS) together with neuropsychological examination of executive functions and memory, was used to investigate a collective of 31 male amateur boxers and 31 age-matched controls as well as a subgroup of 19 individuals, respectively, who were additionally matched for intellectual performance (IQ).

resultsAll participants had normal findings in neurological examination and conventional MR. Amateur boxers did not show deficits in neuropsychological tests when their IQ was taken into account. Fractional anisotropy was significantly reduced, while diffusivity measures were increased along central white matter tracts in the boxers group. These changes were in part associated with the number of fights.

conclusionsTBSS revealed widespread white matter disturbance partially related to the individual fighting history in amateur boxers. These findings closely resemble those in patients with accidental TBI and indicate similar histological changes in amateur boxers.

Indexed as

AdultBoxingBrainChronic Traumatic EncephalopathyDiffusion Tensor ImagingHumansLeukoencephalopathiesMaleReproducibility of ResultsSensitivity and SpecificityWhite MatterDiffusion tensor imagingNeuropsychologyOlympic boxingTraumatic brain injuryWhite matter disturbance

Identifiers

PMID27230917
OpenAlexW2395838046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.