ArticleGenome biology2016
Computing tumor trees from single cells.
Article in Genome biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Article
- Sc-TUSV-Ext: Single-Cell Clonal Lineage Inference from Single Nucleotide Variants, Copy Number Alterations, and Structural Variants.Journal of computational biology : a journal of computational molecular cell biology · 2025Article
- Assessing the performance of methods for cell clustering from single-cell DNA sequencing data.PLoS computational biology · 2023Article
- Specific gut microbiome signature predicts hepatitis B virus-related hepatocellular carcinoma patients with microvascular invasion.Annals of medicine · 2023Article
- Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics.Nature reviews. Genetics · 2021Review
- Power and pitfalls of computational methods for inferring clone phylogenies and mutation orders from bulk sequencing data.Scientific reports · 2020Article
- Measuring single cell divisions in human tissues from multi-region sequencing data.Nature communications · 2020Article
- Algorithmic approaches to clonal reconstruction in heterogeneous cell populations.Quantitative biology (Beijing, China) · 2019Article
- SiCloneFit: Bayesian inference of population structure, genotype, and phylogeny of tumor clones from single-cell genome sequencing data.Genome research · 2019Article
- Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data.Nature communications · 2019Article
- Learning mutational graphs of individual tumour evolution from single-cell and multi-region sequencing data.BMC bioinformatics · 2019Article
- Assessing reliability of intra-tumor heterogeneity estimates from single sample whole exome sequencing data.PloS one · 2019Article
- Detecting repeated cancer evolution from multi-region tumor sequencing data.Nature methods · 2018Article
- Phylogenetic Copy-Number Factorization of Multiple Tumor Samples.Journal of computational biology : a journal of computational molecular cell biology · 2018Article
- Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations.Diagnostics (Basel, Switzerland) · 2018Review
- Beyond Enumeration: Functional and Computational Analysis of Circulating Tumor Cells to Investigate Cancer Metastasis.Frontiers in medicine · 2018Review
- Classifying the evolutionary and ecological features of neoplasms.Nature reviews. Cancer · 2017Review
- SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models.Genome biology · 2017Article
- Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer.Genome research · 2017Article
- Challenges and unanswered questions for the next decade of circulating tumour cell research in lung cancer.Translational lung cancer research · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Computational methods have been developed to reconstruct evolutionary lineages from tumors using single-cell genomic data. The resulting tumor trees have important applications in cancer research and clinical oncology.Please see related Research articles: http://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0929-9 and http://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0936-x .
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.