Evidence map›Paper›PMID 27230672›Full record

ReviewBMC cell biology2016

Connexins and pannexins in neuronal development and adult neurogenesis.

Leigh Anne Swayne, Steffany A L Bennett

Open access · goldAbstract readReview
In one paragraph

Review in BMC cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 57 citations in OpenAlex.

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  17. Development, Diversity, and Death of MGE-Derived Cortical Interneurons.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Review
  20. The Roles of Calmodulin and CaMKII in Cx36 Plasticity.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Leigh Anne SwayneDivision of Medical Sciences, University of Victoria, Medical Sciences Building Rm 224, 3800 Finnerty Rd, Victoria, BC, V8P5C2, Canada. lswayne@uvic.ca.
Steffany A L BennettDepartment of Biochemistry, Microbiology and Immunology, Neural Regeneration Laboratory, Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada.
University of Ottawa · CAUniversity of Victoria · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Connexins and pannexins share very similar structures and functions; they also exhibit overlapping expression in many stages of neuronal development. Here, we review evidence implicating connexin- and pannexin-mediated communication in the regulation of the birth and development of neurons, specifically Cx26, Cx30, Cx32, Cx36, Cx43, Cx45, Panx1, and Panx2. We begin by dissecting the involvement of these proteins in the generation and development of new neurons in the embryonic, postnatal, and adult brain. Next we briefly outline common mechanisms employed by both pannexins and connexins in these roles, including modulation of purinergic receptor signalling and signalling nexus functions. Throughout this review we highlight developing themes as well as important gaps in knowledge to be bridged.

Indexed as

NeurogenesisAdultAnimalsBrainConnexinsHumansNerve Tissue ProteinsNeural Stem CellsNeuronsConnexinsNerve Tissue Proteins

Identifiers

PMID27230672
PMCPMC4896249
OpenAlexW2407387971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.