Evidence map›Paper›PMID 27230564›Full record

ReviewCritical care (London, England)2016

Diagnosis and management of invasive candidiasis in the ICU: an updated approach to an old enemy.

Thierry Calandra, Jason A Roberts, Massimo Antonelli, Matteo Bassetti, Jean-Louis Vincent

Abstract readReview
In one paragraph

Review in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Overview of Risk Factors and Diagnosis of Invasive Candidiasis.Journal of fungi (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Early-Onset Candidemia in Adult Intensive Care Units.Diagnostics (Basel, Switzerland) · 2025
    Review
  14. Role of liposomal amphotericin B in intensive care unit: an expert opinion paper.Journal of anesthesia, analgesia and critical care · 2025
    Review
  15. Invasive Candidiasis in the Intensive Care Unit: Where Are We Now?Journal of fungi (Basel, Switzerland) · 2025
    Review
  16. Review
  17. Review
  18. Journal of fungi (Basel, Switzerland) · 2024
    Article
  19. Article
  20. Observational

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thierry CalandraInfectious Diseases Service, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
Jason A RobertsBurns, Trauma and Critical Care Research Centre, The University of Queensland, Royal Brisbane and Women's Hospital, Butterfield Street, 4029 Herston, Brisbane, Australia.
Massimo AntonelliDepartment of Anesthesiology and Intensive Care Medicine, Catholic University of Rome, A. Gemelli University Hospital, Largo A. Gemelli 8, 00168, Rome, Italy.
Matteo BassettiInfectious Diseases Division, Santa Maria Misericordia University Hospital, Piazzale Santa MAria della Misericordia 15, 33100, Udine, Italy.
Jean-Louis VincentDepartment of Intensive Care, Erasme Hospital, Université libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium. jlvincent@intensive.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive fungal infections, particularly those caused by Candida species, are not uncommon in critically ill patients and are associated with considerable morbidity and mortality. Diagnosis and management of these infections can be challenging. In this review, we will briefly discuss recent epidemiological data on invasive candidiasis and current diagnostic approaches before concentrating on antifungal treatments.

Indexed as

Disease ManagementIntensive Care UnitsAntifungal AgentsCandida albicansCandidiasisFluconazoleHumansTriazolesAntifungal AgentsFluconazoleTriazoles

Identifiers

PMID27230564
PMCPMC4882871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.