ArticleBMC genomics2016
Molecular phylogeny and dynamic evolution of disease resistance genes in the legume family.
Article in BMC genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 72 citations in OpenAlex.
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- LDRGDb - Legumes disease resistance genes database.Frontiers in plant science · 2023Article
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- Progress in soybean functional genomics over the past decade.Plant biotechnology journal · 2022Review
- Genome-Wide Identification, Characterization, and Comparative Analysis ofFrontiers in plant science · 2022Article
- The genome of the rice variety LTH provides insight into its universal susceptibility mechanism to worldwide rice blast fungal strains.Computational and structural biotechnology journal · 2022Article
- Tandem Protein Kinases Emerge as New Regulators of Plant Immunity.Molecular plant-microbe interactions : MPMI · 2021Review
- Novel disease resistance gene paralogs created by CRISPR/Cas9 in soy.Plant cell reports · 2021Article
- Comparison and evolutionary analysis of Brassica nucleotide binding site leucine rich repeat (NLR) genes and importance for disease resistance breeding.The plant genome · 2021Review
- Orthology and synteny analysis of receptor-like kinases "RLK" and receptor-like proteins "RLP" in legumes.BMC genomics · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLegumes are the second-most important crop family in agriculture for its economic and nutritional values. Disease resistance (R-) genes play an important role in responding to pathogen infections in plants. To further increase the yield of legume crops, we need a comprehensive understanding of the evolution of R-genes in the legume family.
resultsIn this study, we developed a robust pipeline and identified a total of 4,217 R-genes in the genomes of seven sequenced legume species. A dramatic diversity of R-genes with structural variances indicated a rapid birth-and-death rate during the R-gene evolution in legumes. The number of R-genes transiently expanded and then quickly contracted after whole-genome duplications, which meant that R-genes were sensitive to subsequent diploidization. R proteins with the Coiled-coil (CC) domain are more conserved than others in legumes. Meanwhile, other types of legume R proteins with only one or two typical domains were subjected to higher rates of loss during evolution. Although R-genes evolved quickly in legumes, they tended to undergo purifying selection instead of positive selection during evolution. In addition, domestication events in some legume species preferentially selected for the genes directly involved in the plant-pathogen interaction pathway while suppressing those R-genes with low occurrence rates.
conclusionsOur results provide insights into the dynamic evolution of R-genes in the legume family, which will be valuable for facilitating genetic improvements in the disease resistance of legume cultivars.
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