ArticleChemical reviews2016
Crystal Nucleation in Liquids: Open Questions and Future Challenges in Molecular Dynamics Simulations.
Article in Chemical reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
131 citing papers in PubMed.
- Universal crystallization kinetics of solution-processed semiconductors.Nature communications · 2026Article
- Boron-assisted synthesis of compositionally complex amorphous oxides via short-range-order-constrained generative design.Science advances · 2026Article
- Computational Methods for Molecular Dynamics of Supercooled Water Between 200 and 273 K.Entropy (Basel, Switzerland) · 2026Review
- Predicting phase transitions across temperature, pressure, and chemical potential using exponentially tilted thermodynamic maps.Nature communications · 2026Article
- Crystal nucleation and growth in high-entropy alloys revealed by atomic electron tomography.Nature materials · 2026Article
- Macroscopic chirogenesis and photoinduced chiral motions enabled by selective accommodation of protic guests.Nature communications · 2026Article
- Substrate-Assisted Flux Method for Robust Synthesis of Quantum-Grade Transition Metal Dichalcogenides.Small methods · 2026Article
- Interfacial Nucleation Pathways Governing Polymorph Selection Revealed by Synchrotron-BasedJournal of the American Chemical Society · 2026Article
- Artificial Intelligence-Guided Cosolvent Design for High-Performance Perovskite/Silicon Tandem Solar Cells.Nano-micro letters · 2026Article
- Rapid Exploration of Mixture Adsorption via Adiabatic Sampling.The journal of physical chemistry. C, Nanomaterials and interfaces · 2026Article
- Understanding the precipitation mechanism in pentavalent vanadium electrolytes through deep learning potential molecular dynamics.Chemical science · 2026Article
- Hybrid Polymer-Inorganic Salt Hydrate Materials: Applications for Heat Storage and Beyond.ACS applied materials & interfaces · 2026Review
- Competing structural orders frustrate crystallization in a metallic glass.Nature communications · 2026Article
- Sub-Ångström Three-Dimensional Electron Diffraction Reveals Crystal Structures and Phase Transformations in Liquids.Journal of the American Chemical Society · 2026Article
- Narrowing down the cause of the hard-sphere nucleation discrepancy: The free energy of precritical nuclei is consistent with predictions.Science advances · 2026Article
- Structural Design of Bismuth Telluride Nanoplates through Process Variables.Chemistry of materials : a publication of the American Chemical Society · 2026Article
- Article
- Thermophysical properties and solidification behavior of liquid Vit106a in microgravity.NPJ microgravity · 2026Article
- The role of fluctuations in the nucleation process.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The nucleation of crystals in liquids is one of nature's most ubiquitous phenomena, playing an important role in areas such as climate change and the production of drugs. As the early stages of nucleation involve exceedingly small time and length scales, atomistic computer simulations can provide unique insights into the microscopic aspects of crystallization. In this review, we take stock of the numerous molecular dynamics simulations that, in the past few decades, have unraveled crucial aspects of crystal nucleation in liquids. We put into context the theoretical framework of classical nucleation theory and the state-of-the-art computational methods by reviewing simulations of such processes as ice nucleation and the crystallization of molecules in solutions. We shall see that molecular dynamics simulations have provided key insights into diverse nucleation scenarios, ranging from colloidal particles to natural gas hydrates, and that, as a result, the general applicability of classical nucleation theory has been repeatedly called into question. We have attempted to identify the most pressing open questions in the field. We believe that, by improving (i) existing interatomic potentials and (ii) currently available enhanced sampling methods, the community can move toward accurate investigations of realistic systems of practical interest, thus bringing simulations a step closer to experiments.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.