Evidence map›Paper›PMID 27228391›Full record

ArticleNanoscale2016

Magnetically-responsive silica-gold nanobowls for targeted delivery and SERS-based sensing.

Alexander H Mo, Preston B Landon, Karla Santacruz Gomez, Heemin Kang, Joon Lee, Chen Zhang, Woraphong Janetanakit, Vrinda Sant, Tianyu Lu, David A Colburn and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Static and Dynamic Biomaterial Engineering for Cell Modulation.Nanomaterials (Basel, Switzerland) · 2022
    Review
  4. Review
  5. Article
  6. Magnetic Nanoparticle Composites: Synergistic Effects and Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  7. Review
  8. Nanobottles for Controlled Release and Drug Delivery.Advanced healthcare materials · 2021
    Review
  9. Magneto-Optical Nanostructures for Viral Sensing.Nanomaterials (Basel, Switzerland) · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Alexander H MoMaterials Science and Engineering Program, La Jolla, CA 92093, USA. rlal@ucsd.edu.
Preston B LandonDept. of Bioengineering, La Jolla, CA 92093, USA. plandon@ucsd.edu and Dept. of Mechanical and Aerospace Engineering & Institute of Engineering in Medicine, La Jolla, CA 92093, USA.
Karla Santacruz GomezDept. of Mechanical and Aerospace Engineering & Institute of Engineering in Medicine, La Jolla, CA 92093, USA and Departamento de Física, Universidad de Sonora, Hermosillo, Sonora, México.
Heemin KangMaterials Science and Engineering Program, La Jolla, CA 92093, USA. rlal@ucsd.edu and Dept. of Bioengineering, La Jolla, CA 92093, USA. plandon@ucsd.edu.
Joon LeeMaterials Science and Engineering Program, La Jolla, CA 92093, USA. rlal@ucsd.edu.
Chen ZhangDept. of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Woraphong JanetanakitDept. of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Vrinda SantDept. of Bioengineering, La Jolla, CA 92093, USA. plandon@ucsd.edu.
Tianyu LuDept. of Bioengineering, La Jolla, CA 92093, USA. plandon@ucsd.edu.
David A ColburnDept. of Bioengineering, La Jolla, CA 92093, USA. plandon@ucsd.edu.
Siddhartha AkkirajuDept. of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Samuel DossouDept. of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Yue CaoDept. of Bioengineering, La Jolla, CA 92093, USA. plandon@ucsd.edu.
Kuo-Fen LeeSalk Institute for Biological Studies, La Jolla, CA 92037, USA.
Shyni VargheseMaterials Science and Engineering Program, La Jolla, CA 92093, USA. rlal@ucsd.edu and Dept. of Bioengineering, La Jolla, CA 92093, USA. plandon@ucsd.edu and Dept. of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Gennadi GlinskyDept. of Mechanical and Aerospace Engineering & Institute of Engineering in Medicine, La Jolla, CA 92093, USA.
Ratnesh LalMaterials Science and Engineering Program, La Jolla, CA 92093, USA. rlal@ucsd.edu and Dept. of Bioengineering, La Jolla, CA 92093, USA. plandon@ucsd.edu and Dept. of Mechanical and Aerospace Engineering & Institute of Engineering in Medicine, La Jolla, CA 92093, USA.

Funding

Designing an Integrated Nanoscale System for Ion Channel Structure-Function StudyR01DA025296 · NIDA · UNIVERSITY OF CHICAGO · PI LAL, RATNESHWAR · 2008 to 2013
$1.7M
Structure, Activity & Physiological Role of HemichannelsR01DA024871 · NIDA · UNIVERSITY OF CHICAGO · PI LAL, RATNESHWAR · 2008 to 2012
$1.5M
NIDA NIH HHS R01 DA024871NIDA NIH HHS R01 DA025296
6 · The paper itself

Abstract

Composite colloidal structures with multi-functional properties have wide applications in targeted delivery of therapeutics and imaging contrast molecules and high-throughput molecular bio-sensing. We have constructed a multifunctional composite magnetic nanobowl using the bottom-up approach on an asymmetric silica/polystyrene Janus template consisting of a silica shell around a partially exposed polystyrene core. The nanobowl consists of a silica bowl and a gold exterior shell with iron oxide magnetic nanoparticles sandwiched between the silica and gold shells. The nanobowls were characterized by electron microscopy, atomic force microscopy, magnetometry, vis-NIR and FTIR spectroscopy. Magnetically vectored transport of these nanobowls was ascertained by time-lapsed imaging of their flow in fluid through a porous hydrogel under a defined magnetic field. These magnetically-responsive nanobowls show distinct surface enhanced Raman spectroscopy (SERS) imaging capability. The PEGylated magnetically-responsive nanobowls show size-dependent cellular uptake in vitro.

Indexed as

Spectrum Analysis, RamanCell Line, TumorGoldHumansNanoparticlesPolystyrenesSilicon DioxideGoldPolystyrenesSilicon Dioxide

Identifiers

PMID27228391
PMCPMC6295298

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.