ReviewExpert review of neurotherapeutics2016
Deep brain stimulation for the treatment of uncommon tremor syndromes.
Review in Expert review of neurotherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Deep brain stimulation in uncommon tremor disorders: indications, targets, and programming.Journal of neurology · 2018Pooled it
- Deep Brain Stimulation in Classical Galactosemia: A Case-Report.Movement disorders clinical practice · 2025Article
- Thalamic deep brain stimulation for postural tremor caused by hyperthermia-induced cerebellar dysfunction: A case report.eNeurologicalSci · 2024Article
- Thalamic ventral-Oralis complex/rostral zona incerta deep brain stimulation for midline tremor.Journal of neurology · 2024Article
- Unilateral deep brain stimulation (DBS) of nucleus ventralis intermedius thalami (Vim) for the treatment of post-traumatic tremor in children: a multicentre experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Validation and application of computer vision algorithms for video-based tremor analysis.NPJ digital medicine · 2024Article
- Linking the cerebellum to Parkinson disease: an update.Nature reviews. Neurology · 2023Review
- DBS in tremor with dystonia: VIM, GPi or both? A review of the literature and considerations from a single-center experience.Journal of neurology · 2023Review
- Progressive Multifocal Encephalopathy Holmes Tremor Successfully Treated with Bilateral Deep Brain Stimulation.Tremor and other hyperkinetic movements (New York, N.Y.) · 2023Article
- Medical and Surgical Treatment for Medication-Induced Tremor: Case Report and Systematic Review.Movement disorders clinical practice · 2022Review
- Deep brain stimulation of the posterior subthalamic area as an alternative strategy for management of Holmes tremor: A case report and review of the literature.Surgical neurology international · 2022Article
- Evolving Concepts in Our Understanding and Treatment of Holmes Tremor, Over 100 Years in the Making.Tremor and other hyperkinetic movements (New York, N.Y.) · 2022Review
- Deep Brain Stimulation for Tremor: Update on Long-Term Outcomes, Target Considerations and Future Directions.Journal of clinical medicine · 2021Review
- Case Report: Dual Target Deep Brain Stimulation With Externalized Programming for Post-traumatic Complex Movement Disorder.Frontiers in neuroscience · 2021Article
- Thalamic Deep Brain Stimulation for Refractory Atypical Tremor after Encephalitis of Unknown Etiology: A Case Report.NMC case report journal · 2021Article
- Deep brain stimulation in essential tremor: targets, technology, and a comprehensive review of clinical outcomes.Expert review of neurotherapeutics · 2020Review
- Waldenstrom-associated anti-MAG paraprotein polyneuropathy with neurogenic tremor.BMJ case reports · 2019Article
- Treatment with Botulinum Neurotoxin Improves Activities of Daily Living and Quality of Life in Patients with Upper Limb Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2019Article
- Is deep brain stimulation therapy underutilized for movement disorders?Expert review of neurotherapeutics · 2018Article
- [Rare tremor syndromes].Der Nervenarzt · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
introductionDeep brain stimulation (DBS) has become a standard therapy for the treatment of select cases of medication refractory essential tremor and Parkinson's disease however the effectiveness and long-term outcomes of DBS in other uncommon and complex tremor syndromes has not been well established. Traditionally, the ventralis intermedius nucleus (VIM) of the thalamus has been considered the main target for medically intractable tremors; however alternative brain regions and improvements in stereotactic techniques and hardware may soon change the horizon for treatment of complex tremors. AREAS COVERED: In this article, we conducted a PubMed search using different combinations between the terms 'Uncommon tremors', 'Dystonic tremor', 'Holmes tremor' 'Midbrain tremor', 'Rubral tremor', 'Cerebellar tremor', 'outflow tremor', 'Multiple Sclerosis tremor', 'Post-traumatic tremor', 'Neuropathic tremor', and 'Deep Brain Stimulation/DBS'. Additionally, we examined and summarized the current state of evolving interventions for treatment of complex tremor syndromes. Expert commentary: Recently reported interventions for rare tremors include stimulation of the posterior subthalamic area, globus pallidus internus, ventralis oralis anterior/posterior thalamic subnuclei, and the use of dual lead stimulation in one or more of these targets. Treatment should be individualized and dictated by tremor phenomenology and associated clinical features.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.