Evidence map›Paper›PMID 27228158›Full record

ArticlePloS one2016

Base Rates of Depressive Symptoms in Patients with Coronary Heart Disease: An Individual Symptom Analysis.

Sebastian Kohlmann, Benjamin Gierk, Alexandra M Murray, Arne Scholl, Marco Lehmann, Bernd Löwe

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Pharmacogenomics · 2019
    Observational
  3. Symptom patterns and clinical outcomes in women versus men with systolic heart failure and depression.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sebastian KohlmannDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, and Schön Clinic Hamburg-Eilbek, Hamburg, Germany.
Benjamin GierkDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, and Schön Clinic Hamburg-Eilbek, Hamburg, Germany.
Alexandra M MurrayDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, and Schön Clinic Hamburg-Eilbek, Hamburg, Germany.
Arne SchollDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, and Schön Clinic Hamburg-Eilbek, Hamburg, Germany.
Marco LehmannDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, and Schön Clinic Hamburg-Eilbek, Hamburg, Germany.
Bernd LöweDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, and Schön Clinic Hamburg-Eilbek, Hamburg, Germany.
Schön Klinik Hamburg Eilbek · DEAsklepios Kliniken Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMajor depression is common in coronary heart disease (CHD) but challenging to diagnose. Instead of focusing on the overall diagnosis of depression, base rates of depressive symptoms could facilitate screening and management of psychopathology in CHD. The present study investigates the frequency of individual depressive symptoms in CHD and their impact on cardiac and subjective health.

methodsIn total, 1337 in- and outpatients with CHD were screened for depressive symptoms with the Patient Health Questionnaire-9 (PHQ-9) at three different cardiac treatment sites. Tables stratified by age and gender were designed to illustrate base rates of depressive symptoms. Multiple regression analyses adjusted for sociodemographic and clinical data were conducted to test associations between individual depressive symptoms and quality of life as well impairment caused angina pectoris and dyspnea.

resultsDuring the last 14 days, more than half of patients reported a loss of energy (74.9%, 95% Confidence Interval (CI): 70.6-79.2), sleeping problems (69.4%, 95% CI: 64.9-74.0), loss of interest (55.7%, 95% CI: 50.8-60.7). In contrast, psychomotor change (25.6%, 95%CI: 21.3-30.0), feelings of failure (21.9%, 95%CI: 17.7-26.0), suicidal ideations (14.1%, 95%CI: 10.7-17.6) were less frequently reported. Depending on the outcome, only particular depressive symptoms were highly associated with low quality of life and impairment caused by angina pectoris and dyspnea. Loss of energy was the only depressive symptom that reliably predicted all three outcomes.

conclusionsDepressive symptoms in CHD are frequent but vary widely in terms of frequency. Findings underline the differential effects of individual depressive symptoms on cardiac health. Presented base rates of depressive symptoms offer clinicians a new way to judge the severity of individual depressive symptoms and to communicate individual PHQ-9 profiles with patients with respect to gender, age, cardiac symptoms and quality of life.

Indexed as

Quality of LifeAgedCoronary DiseaseCross-Sectional StudiesDepressive DisorderFemaleHealth StatusHumansMaleMiddle AgedSickness Impact ProfileSurveys and Questionnaires

Identifiers

PMID27228158
PMCPMC4881911
OpenAlexW2401666698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.