Evidence map›Paper›PMID 27228123›Full record

ArticlePediatric pulmonology2016

Bronchiolitis: Analysis of 10 consecutive epidemic seasons.

Giulia Cangiano, Raffaella Nenna, Antonella Frassanito, Melania Evangelisti, Ambra Nicolai, Carolina Scagnolari, Alessandra Pierangeli, Guido Antonelli, Paola Papoff, Laura Petrarca and 3 more

Abstract read
In one paragraph

Article in Pediatric pulmonology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Age and respiratory syncytial virus etiology in bronchiolitis clinical outcomes.The journal of allergy and clinical immunology. Global · 2022
    Article
  16. Article
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  18. Racial and ethnic disparities in bronchiolitis management in freestanding children's hospitals.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2021
    Article
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Giulia CangianoDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.
Raffaella NennaDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.
Antonella FrassanitoDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.
Melania EvangelistiDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.
Ambra NicolaiDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.
Carolina ScagnolariDepartment of Molecular Medicine, Virology Laboratory, "Sapienza" University of Rome, Rome, Italy.
Alessandra PierangeliDepartment of Molecular Medicine, Virology Laboratory, "Sapienza" University of Rome, Rome, Italy.
Guido AntonelliDepartment of Molecular Medicine, Virology Laboratory, "Sapienza" University of Rome, Rome, Italy.
Paola PapoffDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.
Laura PetrarcaDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.
Paolo CapocacciaDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.
Corrado MorettiDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.
Fabio MidullaDepartment of Pediatrics and Infantile Neuropsychiatry, "Sapienza" University of Rome, V.le Regina Elena 324, Rome 00161, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchiolitis is the leading cause of hospitalization in infants under 12 months. Our aims were to analyze epidemiological characteristics of infants with bronchiolitis over 10 consecutive seasons and to evaluate whether there are any clinical differences between infants hospitalized for bronchiolitis during epidemic peak months and infants in non-peak months. We enrolled consecutive enrolled 723 previously healthy term infants hospitalized at the Paediatric Emergency Department, "Sapienza" University of Rome over the period 2004-2014. Fourteen respiratory viruses were detected from nasopharyngeal aspirates by molecular methods. Clinical and demographic data were extracted from clinical charts. Viruses were detected in 351 infants (48.5%): RSV in 234 (32.4%), RV in 44 (6.1%), hBoV in 11 (1.5%), hMPV in 12 (1.6%), co-infections in 39 (5.4%), and other viruses in 11 (1.5%). Analyzing the 10 epidemic seasons, we found higher incidence for bronchiolitis every 4 years with a peak during the months December-January. Infants hospitalized during peak months had lower family history for asthma (P = 0.003), more smoking mothers during pregnancy (P = 0.036), were slightly higher breastfed (0.056), had lower number of blood eosinophils (P = 0.015) and had a higher clinical severity score (P = 0.017). RSV was detected mostly during peak months, while RV was equally distributed during the seasons. We found some variations in bronchiolitis incidence during epidemics, and discriminative characteristics in infants hospitalized for bronchiolitis during peak months and in non-peak months, that might reflect two different populations of children. Pediatr Pulmonol. 2016;51:1330-1335. © 2016 Wiley Periodicals, Inc.

Indexed as

EpidemicsBronchiolitisBronchiolitis, ViralCoinfectionFemaleHospitalizationHuman bocavirusHumansIncidenceInfantInfant, NewbornInfluenza, HumanItalyMaleMetapneumovirusParamyxoviridae Infectionsbronchiolitisepidemicsinfantsvirus

Identifiers

PMID27228123
PMCPMC7167938

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.