Observational studyPloS one2016
Type of Referral, Dialysis Start and Choice of Renal Replacement Therapy Modality in an International Integrated Care Setting.
Observational study in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Early versus late nephrology referral and patient outcomes in chronic kidney disease: an updated systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- Examining factors associated with catheter-defined unplanned dialysis initiation: a UK Renal Registry analysis.Clinical kidney journal · 2026Article
- Urgent Implantation of Peritoneal Dialysis Catheter in Chronic Kidney Disease and Acute Kidney Injury-A Review.Journal of clinical medicine · 2023Review
- Lack or insufficient predialysis nephrology care worsens the outcomes in dialyzed patients - call for action.Renal failure · 2022Article
- Effects of renin-angiotensin system inhibitors on the incidence of unplanned dialysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Preexisting comorbidities are associated with the mortality rate as well as the predialysis adverse events in incident dialysis patients.Kidney research and clinical practice · 2021Article
- Early Referral to Nephrological Care and the Uptake of Peritoneal Dialysis. An Analysis of German Claims Data.International journal of environmental research and public health · 2021Article
- Suboptimal dialysis initiation is associated with comorbidities and uraemia progression rate but not with estimated glomerular filtration rate.Clinical kidney journal · 2021Article
- Risk Factors for Unplanned Dialysis Initiation: A Systematic Review of the Literature.Canadian journal of kidney health and disease · 2019Article
- Optimal start in dialysis shows increased survival in patients with chronic kidney disease.PloS one · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIntegrated Care Settings (ICS) provide a holistic approach to the transition from chronic kidney disease into renal replacement therapy (RRT), offering at least both types of dialysis.
objectivesTo analyze which factors determine type of referral, modality provision and dialysis start on final RRT in ICS clinics.
methodsRetrospective analysis of 626 patients starting dialysis in 25 ICS clinics in Poland, Hungary and Romania during 2012. Scheduled initiation of dialysis with a permanent access was considered as planned RRT start.
resultsModality information (80% of patients) and renal education (87%) were more frequent (p<0.001) in Planned (P) than in Non-Planned (NP) start. Median time from information to dialysis start was 2 months. 89% of patients started on hemodialysis, 49% were referred late to ICS (<3 months from referral to RRT) and 58% were NP start. Late referral, non-vascular renal etiology, worse clinical status, shorter time from information to RRT and less peritoneal dialysis (PD) were associated with NP start (p<0.05). In multivariate logistic regression analysis, P start (p≤0.05) was associated with early referral, eGFR >8.2 ml/min, >2 months between information and RRT initiation and with vascular etiology after adjustment for age and gender. "Optimal care," defined as ICS follow-up >12 months plus modality information and P start, occurred in 23%.
conclusionsDespite the high rate of late referrals, information and education were widely provided. However, NP start was high and related to late referral and may explain the low frequency of PD.
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