Evidence map›Paper›PMID 27228088›Full record

ArticleMagnetic resonance in medicine2016

Accelerated high-bandwidth MR spectroscopic imaging using compressed sensing.

Peng Cao, Peter J Shin, Ilwoo Park, Chloe Najac, Irene Marco-Rius, Daniel B Vigneron, Sarah J Nelson, Sabrina M Ronen, Peder E Z Larson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Fast Imaging for Hyperpolarized MR Metabolic Imaging.Journal of magnetic resonance imaging : JMRI · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peng CaoDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.
Peter J ShinDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.
Ilwoo ParkDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.
Chloe NajacDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.
Irene Marco-RiusDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.
Daniel B VigneronDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.
Sarah J NelsonDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.
Sabrina M RonenDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.
Peder E Z LarsonDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.

Funding

Project 4: Multi-modality Metabolic Imaging for Monitoring Molecular Sub-types of GliomaP01CA118816 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Susan M Chang, Janine Marie Lupo · 2007 to 2026
$44.7M
TR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Daniel B Vigneron · 2011 to 2026
$19.9M
Metabolic Reprogramming in Brain TumorsR01CA172845 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RONEN, SABRINA MIRIAM · 2013 to 2022
$6.3M
MR Metabolic Imaging of Response to Targeted Therapies in GBMR01CA154915 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NELSON, SARAH J., RONEN, SABRINA MIRIAM · 2011 to 2015
$2.7M
Hyperpolarized C-13 Diffusion MRI Measures of Cellular Transport and MetabolismR01EB016741 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LARSON, PEDER ERIC ZUFALL · 2014 to 2017
$2.0M
Hyperpolarized C-13 MR Pulse Sequence Developments for Novel ContrastR00EB012064 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LARSON, PEDER ERIC ZUFALL · 2011 to 2013
$681k
NCI NIH HHS P01 CA118816NCI NIH HHS R01 CA154915NCI NIH HHS R01 CA172845NIBIB NIH HHS P41 EB013598NIBIB NIH HHS R00 EB012064NIBIB NIH HHS R01 EB016741
6 · The paper itself

Abstract

purposeTo develop a compressed sensing (CS) acceleration method with a high spectral bandwidth exploiting the spatial-spectral sparsity of MR spectroscopic imaging (MRSI).

methodsAccelerations were achieved using blip gradients during the readout to perform nonoverlapped and stochastically delayed random walks in kx -ky -t space, combined with block-Hankel matrix completion for efficient reconstruction. Both retrospective and prospective CS accelerations were applied to (13) C MRSI experiments, including in vivo rodent brain and liver studies with administrations of hyperpolarized [1-(13) C] pyruvate at 7.0 Tesla (T) and [2-(13) C] dihydroxyacetone at 3.0 T, respectively.

resultsIn retrospective undersampling experiments using in vivo 7.0 T data, the proposed method preserved spectral, spatial, and dynamic fidelities with R(2) ≥ 0.96 and ≥ 0.87 for pyruvate and lactate signals, respectively, 750-Hz spectral separation, and up to 6.6-fold accelerations. In prospective in vivo experiments, with 3.8-fold acceleration, the proposed method exhibited excellent spatial localization of metabolites and peak recovery for pyruvate and lactate at 7.0 T as well as for dihydroxyacetone and its metabolic products with a 4.5-kHz spectral span (140 ppm at 3.0 T).

conclusionsThis study demonstrated the feasibility of a new CS approach to accelerate high spectral bandwidth MRSI experiments. Magn Reson Med 76:369-379, 2016. © 2016 Wiley Periodicals, Inc.

Indexed as

AlgorithmsBrain ChemistryAnimalsCarbon-13 Magnetic Resonance SpectroscopyData CompressionLiverMagnetic Resonance ImagingMiceMolecular ImagingRatsReproducibility of ResultsSensitivity and Specificitycalibrationless parallel imagingcompressed sensingHankel matrix completionhyperpolarized carbon-13MR spectroscopic imagingrandom blip gradients

Identifiers

PMID27228088
PMCPMC4945498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.