Evidence map›Paper›PMID 27227987›Full record

ReviewThe Journal of the American Academy of Orthopaedic Surgeons2016

AAOS Research Symposium Updates and Consensus: Biologic Treatment of Orthopaedic Injuries.

Robert F LaPrade, Jason L Dragoo, Jason L Koh, Iain R Murray, Andrew G Geeslin, Constance R Chu

Abstract readReviewConsensus Statement
In one paragraph

Review in The Journal of the American Academy of Orthopaedic Surgeons, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Review
  2. Article
  3. Rotator cuff repair and biologic augmentation-what do we know?JSES reviews, reports, and techniques · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Regulatory and Ethical Aspects of Orthobiologic Therapies.Orthopaedic journal of sports medicine · 2022
    Review
  10. Treatment of Muscle Injury with Stem Cells -Revista brasileira de ortopedia · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. The 2020 NBA Orthobiologics Consensus Statement.Orthopaedic journal of sports medicine · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert F LaPradeFrom the Steadman Philippon Research Institute, Vail, CO (Dr. LaPrade), Stanford University, Redwood City, CA (Dr. Dragoo and Dr. Chu), NorthShore University HealthSystem, Chicago, IL (Dr. Koh), the University of Edinburgh, Edinburgh, United Kingdom (Dr. Murray), and Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, MI (Dr. Geeslin).
Jason L Dragoo
Jason L Koh
Iain R Murray
Andrew G Geeslin
Constance R Chu

Funding

Chondrogenesis In SituR01AR051963 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHU, CONSTANCE R · 2007 to 2011
$1.9M
Multicenter Cartilage Repair Preclinical Trial in HorsesRC2AR058929 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHU, CONSTANCE R · 2009 to 2010
$1.7M
2015 AAOS/ORS Biologic Treatments of Orthopaedic Injuries Research SymposiumR13AR067045 · NIAMS · AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS · PI LAPRADE, ROBERT F · 2015 to 2015
$10k
NIAMS NIH HHS R01 AR051963NIAMS NIH HHS R13 AR067045NIAMS NIH HHS RC2 AR058929
6 · The paper itself

Abstract

Strategies that seek to enhance musculoskeletal tissue regeneration and repair by modulating the biologic microenvironment at the site of injury have considerable therapeutic potential. Current and emerging biologic approaches include the use of growth factors, platelet-rich plasma, stem cell therapy, and scaffolds. The American Academy of Orthopaedic Surgeons hosted a research symposium in November 2015 to review the current state-of-the-art biologic treatments of articular cartilage, muscle, tendon, and bone injuries and identify knowledge gaps related to these emerging treatments. This review outlines the findings of the symposium and summarizes the consensus reached on how best to advance research on biologic treatment of orthopaedic injuries.

Indexed as

Biological ProductsCartilage, ArticularCongresses as TopicFractures, BoneHumansMuscle, SkeletalRegenerationTendon InjuriesBiological Products

Identifiers

PMID27227987
PMCPMC6548434

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.