Evidence map›Paper›PMID 27227704›Full record

ArticleCancer medicine2016

Measured cardiorespiratory fitness and self-reported physical activity: associations with cancer risk and death in a long-term prospective cohort study.

Trude E Robsahm, Ragnhild S Falk, Trond Heir, Leiv Sandvik, Linda Vos, Jan E Erikssen, Steinar Tretli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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  16. Fatness and Fitness With Cardiometabolic Risk Factors in Adolescents.The Journal of clinical endocrinology and metabolism · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Trude E RobsahmDepartment of Research, Cancer Registry of Norway, PB 5313 Majorstuen, Oslo, N-0304, Norway.
Ragnhild S FalkOslo centre for biostatistics and epidemiology, Oslo University Hospital, Pb 4950 Nydalen, Oslo, 0424, Norway.
Trond HeirOslo Ischemia study, Oslo University Hospital, Oslo, Norway.
Leiv SandvikOslo centre for biostatistics and epidemiology, Oslo University Hospital, Pb 4950 Nydalen, Oslo, 0424, Norway.
Linda VosDepartment of Research, Cancer Registry of Norway, PB 5313 Majorstuen, Oslo, N-0304, Norway.
Jan E ErikssenOslo Ischemia study, Oslo University Hospital, Oslo, Norway.
Steinar TretliDepartment of Research, Cancer Registry of Norway, PB 5313 Majorstuen, Oslo, N-0304, Norway.
Oslo University Hospital · NOCancer Registry of Norway · NONorwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity is inversely associated with risk of some cancers. The relation with cancer-specific death remains uncertain. Mainly, studies on relationships between physical activity and cancer are based on self-reported physical activity (SPA). Hereby, we examined whether measured cardiorespiratory fitness (CRF) is associated with cancer risk, mortality, and case fatality. We also describe relationships between SPA and these outcomes, and between CRF and SPA. A cohort of 1997 healthy Norwegian men, aged 40-59 years at inclusion in 1972-75, was followed throughout 2012. At baseline, CRF was objectively measured. SPA (leisure time and occupational) was obtained through a questionnaire. Relationships between CRF or SPA, and the outcomes were estimated using Cox regression, adjusted for age, body mass index (BMI), and smoking. Pearson correlation coefficients evaluated agreements between CRF and SPA. During follow-up, 758 men were diagnosed with cancer and 433 cancer deaths occurred. Analyses revealed lower cancer risk (Hazard ratio [HR] 0.85, 95% confidence intervals [CI]: 0.68-1.00), mortality (HR 0.68, 95% CI: 0.53-0.88), and case fatality (HR 0.74, 95% CI: 0.57-0.96), in men with high CRF compared to low CRF. Light leisure time SPA was associated with lower cancer risk (HR 0.70, 95% CI: 0.56-0.86) and mortality (HR 0.64 95% CI: 0.49-0.83), whereas strenuous occupational SPA was associated with higher risks (HR 1.42, 95% CI: 1.13-1.78 and HR 1.45, 95% CI: 1.09-1.93). Correlations between CRF and SPA were 0.351 (P < 0.001) and -0.106 (P < 0.001) for leisure time and occupational SPA, respectively. A high midlife CRF may be beneficial for cancer risk, cancer mortality, and case fatality.

Indexed as

Cardiorespiratory FitnessExerciseSelf ReportAdultAgedFemaleHumansMaleMiddle AgedMortalityNeoplasmsProportional Hazards ModelsRisk AssessmentRisk FactorscancerCardiorespiratory fitnessfatalitymortalityphysical activityrisk

Identifiers

PMID27227704
PMCPMC4884631
OpenAlexW2408155307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.