Evidence map›Paper›PMID 27227304›Full record

ReviewMicrobiology spectrum2016

Chronic Bacterial Pathogens: Mechanisms of Persistence.

Mariana X Byndloss, Renee M Tsolis

Abstract readReview
In one paragraph

Review in Microbiology spectrum, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Non-Animals : an open access journal from MDPI · 2024
    Article
  8. Review
  9. ConcurrentmSphere · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Single-cell profiling identifies ACEScience advances · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mariana X ByndlossDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Sacramento, CA 95817.
Renee M TsolisDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Sacramento, CA 95817.
University of California Davis Medical Center · US

Funding

Innate immune sensing of ER stress during bacterial infectionR01AI109799 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI TSOLIS, RENEE M · 2014 to 2024
$3.6M
Detection of bacterial Type IV secretion by the unfolded protein responseR21AI112258 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI TSOLIS, RENEE M · 2014 to 2015
$350k
NIAID NIH HHS R01 AI109799NIAID NIH HHS R21 AI112258
6 · The paper itself

Abstract

Many bacterial pathogens can cause acute infections that are cleared with the onset of adaptive immunity, but a subset of these pathogens can establish persistent, and sometimes lifelong, infections. While bacteria that cause chronic infections are phylogenetically diverse, they share common features in their interactions with the host that enable a protracted period of colonization. This article will compare the persistence strategies of two chronic pathogens from the Proteobacteria, Brucella abortus and Salmonella enterica serovar Typhi, to consider how these two pathogens, which are very different at the genomic level, can utilize common strategies to evade immune clearance to cause chronic intracellular infections of the mononuclear phagocyte system.

Indexed as

AnimalsAntibodies, BacterialBacteriaBacterial InfectionsChronic DiseaseCytokinesHost-Parasite InteractionsHumansImmune EvasionImmune SystemImmunity, InnateMacrophagesAntibodies, BacterialCytokines

Identifiers

PMID27227304
PMCPMC4888878
OpenAlexW2402210086

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.