Evidence map›Paper›PMID 27227302›Full record

ReviewMicrobiology spectrum2016

Staying Alive: Vibrio cholerae's Cycle of Environmental Survival, Transmission, and Dissemination.

Jenna G Conner, Jennifer K Teschler, Christopher J Jones, Fitnat H Yildiz

Abstract readReview
In one paragraph

Review in Microbiology spectrum, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Exploring bet-hedging inmSystems · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. bioRxiv : the preprint server for biology · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Environmental DNA adsorption to chitin can promote horizontal gene transfer by natural transformation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Host-Associated Biofilms:Microorganisms · 2025
    Review
  18. mBio · 2025
    Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jenna G ConnerMicrobiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA 95064.
Jennifer K TeschlerMicrobiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA 95064.
Christopher J JonesMicrobiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA 95064.
Fitnat H YildizMicrobiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA 95064.

Funding

Vibrio cholerae c-diGMP signaling: Motile to biofilm transition and transmissionR01AI102584 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2013 to 2023
$6.5M
Vibrio cholerae biofilms: structure, function, regulation and role in infectionR01AI114261 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2014 to 2024
$5.0M
Smooth to Rugose phase variation in Vibrio choleraeR01AI055987 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2003 to 2019
$4.4M
Vibrio cholerae c-diGMP signaling: motile to biofilm transition and transmissionR56AI102584 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2012 to 2012
$608k
Smooth to Rugose phase variation in Vibrio choleraeR56AI055987 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2008 to 2008
$356k
NIAID NIH HHS R01 AI055987NIAID NIH HHS R01 AI102584NIAID NIH HHS R01 AI114261NIAID NIH HHS R56 AI055987NIAID NIH HHS R56 AI102584
6 · The paper itself

Abstract

Infectious diseases kill nearly 9 million people annually. Bacterial pathogens are responsible for a large proportion of these diseases, and the bacterial agents of pneumonia, diarrhea, and tuberculosis are leading causes of death and disability worldwide. Increasingly, the crucial role of nonhost environments in the life cycle of bacterial pathogens is being recognized. Heightened scrutiny has been given to the biological processes impacting pathogen dissemination and survival in the natural environment, because these processes are essential for the transmission of pathogenic bacteria to new hosts. This chapter focuses on the model environmental pathogen Vibrio cholerae to describe recent advances in our understanding of how pathogens survive between hosts and to highlight the processes necessary to support the cycle of environmental survival, transmission, and dissemination. We describe the physiological and molecular responses of V. cholerae to changing environmental conditions, focusing on its survival in aquatic reservoirs between hosts and its entry into and exit from human hosts.

Indexed as

Adaptation, PhysiologicalAnimalsCholeraDisease OutbreaksEnvironmental MicrobiologyHumansMicrobial ViabilityStress, PhysiologicalVibrio cholerae

Identifiers

PMID27227302
PMCPMC4888910

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.