Evidence map›Paper›PMID 27227106›Full record

ArticleEndoscopy international open2016

Usefulness of virtual chromoendoscopy in the evaluation of subtle small bowel ulcerative lesions by endoscopists with no experience in videocapsule.

Mihai Rimbaş, Denise Carmen Mihaela Zahiu, Andrei Mihai Voiosu, Theodor Alexandru Voiosu, Alina Ana-Maria Zlate, Roxana Dinu, Domenico Galasso, Leonardo Minelli Grazioli, Mariachiara Campanale, Federico Barbaro and 10 more

Open access · goldAbstract read
In one paragraph

Article in Endoscopy international open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Endoscopy in inflammatory bowel disease: from guidelines to real life.Therapeutic advances in gastroenterology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Mihai RimbaşGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania; Internal Medicine Department, Carol Davila University of Medicine, Bucharest, Romania.
Denise Carmen Mihaela ZahiuGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania.
Andrei Mihai VoiosuGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania; Internal Medicine Department, Carol Davila University of Medicine, Bucharest, Romania.
Theodor Alexandru VoiosuGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania; Internal Medicine Department, Carol Davila University of Medicine, Bucharest, Romania.
Alina Ana-Maria ZlateGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania.
Roxana DinuGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania.
Domenico GalassoDigestive Endoscopy Unit, Catholic University, Rome, Italy.
Leonardo Minelli GrazioliDigestive Endoscopy Unit, Catholic University, Rome, Italy.
Mariachiara CampanaleDigestive Endoscopy Unit, Catholic University, Rome, Italy.
Federico BarbaroDigestive Endoscopy Unit, Catholic University, Rome, Italy.
Bogdan Radu MateescuGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania; Internal Medicine Department, Carol Davila University of Medicine, Bucharest, Romania.
Bogdan BusuiocGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania.
Tiberiu IordacheGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania.
Oana DolofanGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania.
Adelina Maria PopescuGastroenterology Department, University Emergency Hospital, Bucharest, Romania.
Vasile Daniel BalabanGastroenterology Department, Emergency Military Hospital, Bucharest, Romania.
Mircea Mihai RaducanInternal Medicine Department, Carol Davila University of Medicine, Bucharest, Romania.
Cristiano SpadaDigestive Endoscopy Unit, Catholic University, Rome, Italy.
Cristian Răsvan BăicuşInternal Medicine Department, Carol Davila University of Medicine, Bucharest, Romania.
Guido CostamagnaDigestive Endoscopy Unit, Catholic University, Rome, Italy.
Carol Davila University of Medicine and Pharmacy · ROSpitalul Clinic Colentina · ROUniversità Cattolica del Sacro Cuore · ITClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND STUDY

aimsIn videocapsule endoscopy examination (VCE), subtle variations in mucosal hue or pattern such as those seen in ulcerations can be difficult to detect, depending on the experience of the reader. Our aim was to test whether virtual chromoendoscopy (VC) techniques, designed to enhance the contrast between the lesion and the normal mucosa, could improve the characterization of ulcerative mucosal lesions. PATIENTS AND

methodsFifteen trainees or young gastroenterologists with no experience in VCE were randomly assigned to evaluate 250 true ulcerative and 100 false ulcerative, difficult-to-interpret small bowel lesions, initially as white light images (WLI) and then, in a second round, with the addition of one VC setting or again as WLI, labeling them as real lesions or artifacts.

resultsOn the overall image evaluation, an improvement in lesion characterization was observed by adding any chromoendoscopy setting, especially Blue mode and FICE 1, with increases in accuracy of 13 % [95 %CI 0.8, 25.3] and 7.1 % [95 %CI - 17.0, 31.3], respectively. However, when only false ulcerative images were considered, with the same presets (Blue mode and FICE 1), there was a loss in accuracy of 10.7 % [95 %CI - 10.9, 32.3] and 7.3 % [95 %CI - 1.3, 16.0], respectively. The interobserver agreement was poor for both readings.

conclusionsVC helps beginner VCE readers correctly categorize difficult-to-interpret small bowel mucosal ulcerative lesions. However, false lesions tend to be misinterpreted as true ulcerative with the same presets. Therefore care is advised in using VC especially under poor bowel preparation.

Identifiers

PMID27227106
PMCPMC4874791
OpenAlexW2361013858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.