Evidence map›Paper›PMID 27227102›Full record

ReviewTemperature (Austin, Tex.)

Characteristics of hyperthermia-induced hyperventilation in humans.

Bun Tsuji, Keiji Hayashi, Narihiko Kondo, Takeshi Nishiyasu

Open access · hybridAbstract readReview
In one paragraph

Review in Temperature (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 47 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Cerebrovascular regulation during heat stress.Experimental physiology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. COInternational journal of environmental research and public health · 2024
    Article
  10. The Impact of Inflammation on Thermal Hyperpnea: Relevance for Heat Stress and Febrile Seizures.American journal of respiratory cell and molecular biology · 2024
    Article
  11. Validity of mental and physical stress models.Neuroscience and biobehavioral reviews · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Bun TsujiInstitute of Health and Sport Sciences, University of Tsukuba, Tsukuba City, Japan; Department of Health Sciences, Prefectural University of Hiroshima, Hiroshima, Japan.
Keiji HayashiJunior College, University of Shizuoka , Shizuoka, Japan.
Narihiko KondoFaculty of Human Development, Kobe University , Kobe, Japan.
Takeshi NishiyasuInstitute of Health and Sport Sciences, University of Tsukuba , Tsukuba City, Japan.
University of Tsukuba · JPKobe University · JPUniversity of Shizuoka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In humans, hyperthermia leads to activation of a set of thermoregulatory responses that includes cutaneous vasodilation and sweating. Hyperthermia also increases ventilation in humans, as is observed in panting dogs, but the physiological significance and characteristics of the hyperventilatory response in humans remain unclear. The relative contribution of respiratory heat loss to total heat loss in a hot environment in humans is small, and this hyperventilation causes a concomitant reduction in arterial CO2 pressure (hypocapnia), which can cause cerebral hypoperfusion. Consequently, hyperventilation in humans may not contribute to the maintenance of physiological homeostasis (i.e., thermoregulation). To gain some insight into the physiological significance of hyperthermia-induced hyperventilation in humans, in this review, we discuss 1) the mechanisms underlying hyperthermia-induced hyperventilation, 2) the factors modulating this response, and 3) the physiological consequences of the response.

Indexed as

heat lossHyperpnearespiratory alkalosis

Identifiers

PMID27227102
PMCPMC4879782
OpenAlexW2281147600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.