ReviewTemperature (Austin, Tex.)
Human whole body cold adaptation.
Review in Temperature (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- Effects of Aquatic Exercise in Post-exercise Hypotension: A Systematic Review and Meta-Analysis.Frontiers in physiology · 2022Pooled it
- Metabolic rate and substrate utilisation resilience in men undertaking polar expeditionary travel.PloS one · 2019Trial
- Using Organoids to Unlock the Potential of Human Torpor for Spaceflight.Current stem cell reports · 2026Article
- Naturally Occurring Variability in the Regulatory Region of theInternational journal of molecular sciences · 2026Article
- Repeated Cold Water Stress Leads to Improvements in Mitochondrial Metabolism of Skeletal Muscles in Rats.Metabolites · 2026Article
- Effects of Aquatic Exercise on Individuals with Hypertension: A Systematic Review.Healthcare (Basel, Switzerland) · 2026Review
- Changes in peripheral IR thermography and energy expenditure on cooling in men and women following sustained strenuous activity in Antarctica.Scientific reports · 2026Article
- Real-time thermoregulatory and cardiovascular monitoring of non-acclimatised mountaineers in extreme cold: a 10-day field expedition study.Frontiers in physiology · 2026Article
- The differential effect of ambient temperature on age-specific and sex-specific mortality in the 300 largest cities of Russia, 2000-19: a first national time-series study.The Lancet. Planetary health · 2025Article
- Recent updates on cold adaptation in population and laboratory studies, including cross-adaptation with nonthermal factors.Journal of physiological anthropology · 2025Review
- Article
- Cold weather operations: Preventive strategies in a military context.Temperature (Austin, Tex.) · 2025Review
- Impact of baseline arterial elasticity (stiffness) on left ventricular functions in healthy subjects exposed to short-term extreme cold.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Ambient temperature and the occurrence of intradialytic hypotension in patients receiving hemodialysis.Clinical kidney journal · 2024Article
- Changes in body composition and average daily energy expenditure of men and women during arduous extended polar travel.PloS one · 2024Article
- Metabolic effects of lipectomy and of adipose tissue transplantation.Obesity (Silver Spring, Md.) · 2023Review
- Acral skin vasoreactivity and thermosensitivity to hand cooling following 5 days of intermittent whole body cold exposure.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Human cold habituation: Physiology, timeline, and modifiers.Temperature (Austin, Tex.) · 2022Review
- Human vulnerability and variability in the cold: Establishing individual risks for cold weather injuries.Temperature (Austin, Tex.) · 2022Review
- Change of pace: How developmental tempo varies to accommodate failed provision of early needs.Neuroscience and biobehavioral reviews · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reviews on whole body human cold adaptation generally do not distinguish between population studies and dedicated acclimation studies, leading to confusing results. Population studies show that indigenous black Africans have reduced shivering thermogenesis in the cold and poor cold induced vasodilation in fingers and toes compared to Caucasians and Inuit. About 40,000 y after humans left Africa, natives in cold terrestrial areas seems to have developed not only behavioral adaptations, but also physiological adaptations to cold. Dedicated studies show that repeated whole body exposure of individual volunteers, mainly Caucasians, to severe cold results in reduced cold sensation but no major physiological changes. Repeated cold water immersion seems to slightly reduce metabolic heat production, while repeated exposure to milder cold conditions shows some increase in metabolic heat production, in particular non-shivering thermogenesis. In conclusion, human cold adaptation in the form of increased metabolism and insulation seems to have occurred during recent evolution in populations, but cannot be developed during a lifetime in cold conditions as encountered in temperate and arctic regions. Therefore, we mainly depend on our behavioral skills to live in and survive the cold.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.