ArticleTemperature (Austin, Tex.)
Thermoregulatory responses in exercising rats: methodological aspects and relevance to human physiology.
Article in Temperature (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- 7 days of L-citrulline supplementation does not improve running performance in the heat whilst in a hypohydrated state.European journal of applied physiology · 2025Trial
- Factors Affecting the Applicability of Infrared Thermography as a Measure of Temperament in Cattle.Veterinary sciences · 2025Article
- Characterization of the Core Temperature Response of Free-Moving Rats to 1.95 GHz Electromagnetic Fields.Bioelectromagnetics · 2025Article
- Human and rat ex vivo sweat glands for the observation of acetylcholine induced intracellular calcium signalling.PloS one · 2025Article
- Lactate shuttling as an allostatic means of thermoregulation in the brain.Frontiers in neuroscience · 2023Article
- Core body temperatures of rats subjected to treadmill exercise to fatigue or exhaustion: The journalTemperature (Austin, Tex.) · 2023Article
- Efficacy and Function of Feathers, Hair, and Glabrous Skin in the Thermoregulation Strategies of Domestic Animals.Animals : an open access journal from MDPI · 2021Review
- Review
- Independent effects of rapid eye movement sleep deprivation and exposure to environmental heat stress on aerobic performance and thermoregulatory responses in exercising rats.Temperature (Austin, Tex.) · 2021Article
- Low-cost, open-source, variable speed and incline treadmill for studying impacts of neonatal locomotion.HardwareX · 2020Article
- Article
- Age-Related Changes in the Thermoregulatory Properties in Bank Voles From a Selection Experiment.Frontiers in physiology · 2020Article
- Control of Body Temperature during Physical Exercise.Arquivos brasileiros de cardiologia · 2019Article
- Thermoregulation in Hypertensive Rats during Exercise: Effects of Physical Training.Arquivos brasileiros de cardiologia · 2019Article
- Self-Paced Free-Running Wheel Mimics High-Intensity Interval Training Impact on Rats' Functional, Physiological, Biochemical, and Morphological Features.Frontiers in physiology · 2019Article
- Pre-exercise exposure to the treadmill setup changes the cardiovascular and thermoregulatory responses induced by subsequent treadmill running in rats.Temperature (Austin, Tex.) · 2018Article
- Physical Exercise-Induced Cardiovascular and Thermoregulatory Adjustments Are Impaired in Rats Subjected to Cutaneous Artery Denervation.Frontiers in physiology · 2018Article
- Physical exercise-induced fatigue: the role of serotonergic and dopaminergic systems.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017Review
- Leptin, adiponectin, and ghrelin responses to endurance exercise in different ambient conditions.Temperature (Austin, Tex.) · 2017Article
- Brazil: What country is this?Temperature (Austin, Tex.)Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rats are used worldwide in experiments that aim to investigate the physiological responses induced by a physical exercise session. Changes in body temperature regulation, which may affect both the performance and the health of exercising rats, are evident among these physiological responses. Despite the universal use of rats in biomedical research involving exercise, investigators often overlook important methodological issues that hamper the accurate measurement of clear thermoregulatory responses. Moreover, much debate exists regarding whether the outcome of rat experiments can be extrapolated to human physiology, including thermal physiology. Herein, we described the impact of different exercise intensities, durations and protocols and environmental conditions on running-induced thermoregulatory changes. We focused on treadmill running because this type of exercise allows for precise control of the exercise intensity and the measurement of autonomic thermoeffectors associated with heat production and loss. Some methodological issues regarding rat experiments, such as the sites for body temperature measurements and the time of day at which experiments are performed, were also discussed. In addition, we analyzed the influence of a high body surface area-to-mass ratio and limited evaporative cooling on the exercise-induced thermoregulatory responses of running rats and then compared these responses in rats to those observed in humans. Collectively, the data presented in this review represent a reference source for investigators interested in studying exercise thermoregulation in rats. In addition, the present data indicate that the thermoregulatory responses of exercising rats can be extrapolated, with some important limitations, to human thermal physiology.
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