ReviewTemperature (Austin, Tex.)
Psychogenic fever: how psychological stress affects body temperature in the clinical population.
Review in Temperature (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.
- Meta-Analysis of Children's Acute Psychological Stress and Action Stress on Immune Function under Microscope Images.Journal of healthcare engineering · 2022Pooled it
- Prolactin receptor signalling contributes to the attenuation of stress-induced hyperthermia during pregnancy.Journal of neuroendocrinology · 2026Article
- Functional Hyperthermia Presenting as Fever of Unknown Origin With Normal Inflammatory Markers in an Adolescent.Journal of general and family medicine · 2026Article
- Carbon Monoxide: A Context-Dependent Regulator of the Stress Axis.Biomolecules · 2026Review
- The effect of spaceflight and simulated microgravity exposure on thermoregulation in humans: a systematic review.NPJ microgravity · 2026Article
- Ethnomedicinal plants and traditional healing practices of indigenous communities in Dan Sub-district, Kap Choeng District, Surin Province, Thailand.Journal of ethnobiology and ethnomedicine · 2026Article
- Sarcolipin-SERCA uncoupling as a plausible heat source for sustaining fever.Frontiers in physiology · 2026Article
- A brain-body perspective on thermoregulatory adaptation.Current biology : CB · 2025Review
- Thermal physiology of open water wetsuited swimming: A cohort study.Temperature (Austin, Tex.) · 2025Article
- Psychogenic fever and neurodevelopmental disorders among Japanese children.BioPsychoSocial medicine · 2024Article
- Huddling substates in mice facilitate dynamic changes in body temperature and are modulated by Shank3b and Trpm8 mutation.Communications biology · 2024Article
- Huddling substates in mice facilitate dynamic changes in body temperature and are modulated byResearch square · 2024Article
- Neural cell-types and circuits linking thermoregulation and social behavior.Neuroscience and biobehavioral reviews · 2024Review
- Behavioural and physiological responses to stressors in sheep with temperament classified by genotype or phenotype.Scientific reports · 2024Article
- Disabling symptoms associated with increased axillary temperature in patients with functional hyperthermia.BioPsychoSocial medicine · 2024Article
- Characteristics of Functional Hyperthermia Detected in an Outpatient Clinic for Fever of Unknown Origin.Journal of clinical medicine · 2024Article
- Sex differences in body temperature and neural power spectra in response to repeated restraint stress.Stress (Amsterdam, Netherlands) · 2024Article
- Functional hyperthermia and comorbid psychiatric disorders.BioPsychoSocial medicine · 2023Article
- 'Functional hyperthermia': a historical overview.BioPsychoSocial medicine · 2023Article
- Catecholamine Variations in Pediatric Gastrointestinal Disorders and Their Neuropsychiatric Expression.Biomedicines · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psychogenic fever is a stress-related, psychosomatic disease especially seen in young women. Some patients develop extremely high core body temperature (Tc) (up to 41°C) when they are exposed to emotional events, whereas others show persistent low-grade high Tc (37-38°C) during situations of chronic stress. The mechanism for psychogenic fever is not yet fully understood. However, clinical case reports demonstrate that psychogenic fever is not attenuated by antipyretic drugs, but by psychotropic drugs that display anxiolytic and sedative properties, or by resolving patients' difficulties via natural means or psychotherapy. Animal studies have demonstrated that psychological stress increases Tc via mechanisms distinct from infectious fever (which requires proinflammatory mediators) and that the sympathetic nervous system, particularly β3-adrenoceptor-mediated non-shivering thermogenesis in brown adipose tissue, plays an important role in the development of psychological stress-induced hyperthermia. Acute psychological stress induces a transient, monophasic increase in Tc. In contrast, repeated stress induces anticipatory hyperthermia, reduces diurnal changes in Tc, or slightly increases Tc throughout the day. Chronically stressed animals also display an enhanced hyperthermic response to a novel stress, while past fearful experiences induce conditioned hyperthermia to the fear context. The high Tc that psychogenic fever patients develop may be a complex of these diverse kinds of hyperthermic responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.