ReviewTemperature (Austin, Tex.)
Responses of the hands and feet to cold exposure.
Review in Temperature (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
56 citing papers in PubMed.
- Preliminary study on the effects of boysenberry juice intake on brown adipose tissue activity in healthy adults.Scientific reports · 2024Trial
- Short-term cocoa bioflavanol supplementation does not improve cold-induced vasodilation in young healthy adults.European journal of applied physiology · 2024Trial
- Heart rate variability and cold-induced vascular dilation after stimulation of two different areas of the ear: a prospective, single-blinded, randomized crossover study.BMC complementary medicine and therapies · 2024Trial
- Hesperetin-7-Nutrients · 2023Trial
- Influence of acute beetroot juice supplementation on cold-induced vasodilation and fingertip rewarming.European journal of applied physiology · 2023Trial
- Effects of acute dietary nitrate supplementation on cold-induced vasodilation in healthy males.European journal of applied physiology · 2021Trial
- Cold-induced vasomotion changes in healthy individuals and patients after median or ulnar nerve repair.Scientific reports · 2026Article
- Network Pharmacology-Based Exploration of Complementary Molecular Mechanisms of Heat-Clearing (Scutellariae Radix, Coptidis Rhizoma) and Blood-Tonifying Herbs (Angelicae Sinensis Radix, Paeoniae Radix Alba) in Cold Hypersensitivity in Hands and Feet.Life (Basel, Switzerland) · 2026Article
- Illusory cold desensitizes touch.bioRxiv : the preprint server for biology · 2026Article
- Thermoregulatory responses to air temperature of -5 °C at different wind speeds: significance of strong wind in a mild cold environment.Journal of physiological anthropology · 2026Article
- Palm Cooling's Heart Rate and Thermal Impact on Exercise in Multiple Sclerosis Patients.Sports medicine international open · 2026Article
- Labour-type physical activity, alcohol use and hypertension in rural older adults in Northeast China.Frontiers in public health · 2026Article
- Cold-induced vasodilation: A meta-analysis.Temperature (Austin, Tex.) · 2026Review
- Adaptive restoration of T-cell motility by cold acclimation through metabolic and transcriptional remodeling.Frontiers in immunology · 2026Article
- Burning fast & slow: a review of the differential metabolic routes of brown adipose tissue activity during cold exposure and their implications for populational variation.Lipids in health and disease · 2025Review
- Article
- Cold Tissue Temperature Decreases Electrocutaneous Sensory Perception and Discriminability.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025Article
- Impact of cold exposure on shift working seafood handlers in Northern Norway: a comparative analysis across work shifts.Journal of occupational medicine and toxicology (London, England) · 2025Article
- Article
- Influence of body dimensions and sex on cold-induced vasodilation.European journal of applied physiology · 2025Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An initial response to whole-body or local exposure of the extremities to cold is a strong vasoconstriction, leading to a rapid decrease in hand and foot temperature. This impairs tactile sensitivity, manual dexterity, and muscle contractile characteristics while increasing pain and sympathetic drive, decreasing gross motor function, occupational performance, and survival. A paradoxical and cyclical vasodilatation often occurs in the fingers, toes, and face, and this has been termed the hunting response or cold-induced vasodilatation (CIVD). Despite being described almost a century ago, the mechanisms of CIVD are still disputed; research in this area has remained largely descriptive in nature. Recent research into CIVD has brought increased standardization of methodology along with new knowledge about the impact of mediating factors such as hypoxia and physical fitness. Increasing mechanistic analysis of CIVD has also emerged along with improved modeling and prediction of CIVD responses. The present review will survey work conducted during this century on CIVD, its potential mechanisms and modeling, and also the broader context of manual function in cold conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.