Evidence map›Paper›PMID 27226934›Full record

ArticleMessenger (Los Angeles, Calif. : Print)2015

Poring over two-pore channel pore mutants.

Christopher J Penny, Sandip Patel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Messenger (Los Angeles, Calif. : Print), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Endo-Lysosomal Two-Pore Channels and Their Protein Partners.Handbook of experimental pharmacology · 2023
    Review
  2. Segregated cation flux by TPC2 biases CaNature communications · 2022
    Article
  3. Review
  4. Two-pore channels and disease.Biochimica et biophysica acta. Molecular cell research · 2018
    Review
  5. Lysosomal Calcium in Neurodegeneration.Messenger (Los Angeles, Calif. : Print) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christopher J PennyDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT.
Sandip PatelDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT.

Funding

Biotechnology and Biological Sciences Research Council BB/G013721/1
6 · The paper itself

Abstract

Two-pore channels are members of the voltage-gated ion channel superfamily. They localise to the endolysosomal system and are likely targets for the Ca

Indexed as

homology modellingNAADPsite-directed mutagenesisstructure-functionTPC1TPC2voltage-gated ion channel

Identifiers

PMID27226934
PMCPMC4876920

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.