Evidence map›Paper›PMID 27226742›Full record

ArticleBotanics : targets and therapy

Recent perspectives on the anticancer properties of aqueous extracts of Nigerian

Carolyn Bingham Howard, William K Johnson, Shehla Pervin, Ernest B Izevbigie

Open access · diamondAbstract read
In one paragraph

Article in Botanics : targets and therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Carolyn Bingham HowardBreast Cancer Research Laboratory, Research Centers in Minority Institutions, Jackson State University, Jackson, MS, USA; Department of Biology, Jackson State University, Jackson, MS, USA; NIH-Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS, USA.
William K JohnsonDepartment of Biology, Jackson State University, Jackson, MS, USA; NIH-Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS, USA.
Shehla PervinDivision of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Charles R Drew University of Medicine and Science, Los Angeles, CA, USA.
Ernest B IzevbigieBenson Idahosa University, Benin City, Edo State, Nigeria.
Benson Idahosa University · NGCharles R. Drew University of Medicine and Science · USJackson State University · US

Funding

TRANSCRIPTOMICS OF GIARDIA LAMBLIAG12RR013459 · NCRR · JACKSON STATE UNIVERSITY · PI GAO, RUOMEI · 1998 to 2011
$18.0M
RCMI-Center for Environmental HealthG12MD007581 · NIMHD · JACKSON STATE UNIVERSITY · PI TCHOUNWOU, PAUL B. · 2012 to 2017
$11.2M
Targeting pERK1/2 in Human Mammary Cancer Stem CellsSC1CA165865 · NCI · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI PERVIN, SHEHLA · 2011 to 2015
$1.4M
NCI NIH HHS SC1 CA165865NCRR NIH HHS G12 RR013459NIMHD NIH HHS G12 MD007581
6 · The paper itself

Abstract

Innovative developments are necessary for treating and defeating cancer, an oftentimes deadly group of diseases characterized by the uncontrolled growth and spread of abnormal cells. Breast cancer (BC) is the second leading cause of cancer-related deaths of women in the USA, and prostate cancer (PC) is the second leading cause of cancer-related deaths of American men. Although some efficacious BC drugs are pharmaceutically marketed, they affect the quality of life for some patients because they are toxic in that their usages have been accompanied by side effects such as stroke, thrombosis, slow heart rate, seizure, increased blood pressure, nausea, emesis, and more. Therefore, there is an urgent need for the discovery of molecular markers for early detection of this disease and discovery of targets for the development of novel, less toxic therapeutics. A botanical plant

Indexed as

anticancer agentsantitumorigenic agentsbreast cancerchemopreventive natural productsprostate cancer

Identifiers

PMID27226742
PMCPMC4876981
OpenAlexW2181821621

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.