Evidence map›Paper›PMID 27226665›Full record

ArticleColombia medica (Cali, Colombia)2016

Clinical outcomes of kidney transplants on patients with end-stage renal disease secondary to lupus nephritis, polycystic kidney disease and diabetic nephropathy.

John Fredy Nieto-Ríos, Lina María Serna-Higuita, Sheila Alexandra Builes-Rodriguez, Ricardo Cesar Restrepo-Correa, Arbey Aristizabal-Alzate, Catalina Ocampo-Kohn, Angélica Serna-Campuzano, Natalia Cardona-Díaz, Nelson Darío Giraldo-Ramirez, Gustavo Adolfo Zuluaga-Valencia

Abstract read
In one paragraph

Article in Colombia medica (Cali, Colombia), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

John Fredy Nieto-RíosSección Nefrología. Hospital Pablo Tobon Uribe, Medellín, Colombia; Sección de Nefrología, Universidad de Antioquia, Medellín, Colombia.
Lina María Serna-HiguitaSección Nefrología. Hospital Pablo Tobon Uribe, Medellín, Colombia; Sección de Pediatría y Puericultura, Universidad de Antioquia. Medellin, Colombia.
Sheila Alexandra Builes-RodriguezSección de Nefrología, Universidad Pontificia Bolivariana, Medellín, Colombia.
Ricardo Cesar Restrepo-CorreaSección de Medicina Interna, Hospital Pablo Tobón Uribe. Medellín, Colombia.
Arbey Aristizabal-AlzateSección Nefrología. Hospital Pablo Tobon Uribe, Medellín, Colombia; Sección de Nefrología, Universidad de Antioquia, Medellín, Colombia.
Catalina Ocampo-KohnSección Nefrología. Hospital Pablo Tobon Uribe, Medellín, Colombia; Sección de Nefrología, Universidad de Antioquia, Medellín, Colombia.
Angélica Serna-CampuzanoSección de Nefrología, Universidad Pontificia Bolivariana, Medellín, Colombia.
Natalia Cardona-DíazSección Nefrología. Hospital Pablo Tobon Uribe, Medellín, Colombia.
Nelson Darío Giraldo-RamirezSección Nefrología. Hospital Pablo Tobon Uribe, Medellín, Colombia.
Gustavo Adolfo Zuluaga-ValenciaSección Nefrología. Hospital Pablo Tobon Uribe, Medellín, Colombia; Sección de Nefrología, Universidad de Antioquia, Medellín, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with lupus nephritis could progress to end-stage renal disease (10-22%); hence, kidney transplants should be considered as the treatment of choice for these patients.

objectiveTo evaluate the clinical outcomes after kidney transplants in patients with chronic kidney diseases secondary to lupus nephritis, polycystic kidney disease and diabetes nephropathy at Pablo Tobon Uribe Hospital.

methodsA descriptive and retrospective study performed at one kidney transplant center between 2005 and 2013.

resultsA total of 136 patients, 27 with lupus nephritis (19.9%), 31 with polycystic kidney disease (22.8%) and 78 with diabetes nephropathy (57.4%), were included in the study. The graft survivals after one, three and five years were 96.3%, 82.5% and 82.5% for lupus nephritis; 90%, 86% and 76.5% for polycystic kidney disease and 91.7%, 80.3% and 67.9% for diabetes nephropathy, respectively, with no significant differences (p= 0.488); the rate of lupus nephritis recurrence was 0.94%/person-year. The etiology of lupus vs diabetes vs polycystic disease was not a risk factor for a decreased time of graft survival (Hazard ratio: 1.43; 95% CI: 0.52-3.93).

conclusionKidney transplant patients with end stage renal disease secondary to lupus nephritis has similar graft and patient survival success rates to patients with other kidney diseases. The complication rate and risk of recurrence for lupus nephritis are low. Kidney transplants should be considered as the treatment of choice for patients with end stage renal disease secondary to lupus nephritis.

Indexed as

Graft SurvivalKidney TransplantationAdultAgedDiabetic NephropathiesFemaleGlomerular Filtration RateGraft RejectionHumansKidney Failure, ChronicLupus NephritisMaleMiddle AgedPolycystic Kidney DiseasesPostoperative ComplicationsRegression Analysisdiabetic nephropathiesKidney transplantationLupus nephritispolycystic kidney diseases

Identifiers

PMID27226665
PMCPMC4867517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.