Observational studyThe British journal of radiology2016
Pulmonary computed tomography findings in patients with chronic aspiration detected by videofluoroscopic swallowing study.
Observational study in The British journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Chest CT findings in patients with dysphagia and aspiration: a systematic review.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaPooled it
- Impact of gastroesophageal reflux on longitudinal lung function and quantitative computed tomography in the COPDGene cohort.Respiratory research · 2020Trial
- Aspiration, respiratory complications, and associated healthcare resource utilization among individuals with Rett syndrome.Orphanet journal of rare diseases · 2025Article
- Gastrointestinal factors associated with risk of bronchiectasis in children.Pediatric pulmonology · 2023Article
- Challenges in the Differential Diagnosis of COVID-19 Pneumonia: A Pictorial Review.Diagnostics (Basel, Switzerland) · 2022Review
- Case Report: Next-Generation Sequencing in Diagnosis of Atypical Aspiration Pneumonia.Frontiers in public health · 2021Article
- Investigation of high-resolution computed tomographic (HRCT) outcomes associated with chronic pulmonary microaspiration (CPM) in Tehran and Zahedan, Iran.African health sciences · 2020Article
- How to detect and track chronic neurologic sequelae of COVID-19? Use of auditory brainstem responses and neuroimaging for long-term patient follow-up.Brain, behavior, & immunity - health · 2020Review
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo demonstrate CT findings in patients with chronic aspiration compared with a control group without aspiration, as detected by the videofluoroscopic swallowing study (VFSS).
methodsThis retrospective, observational study included patients with and without diagnoses of aspiration confirmed by VFSS, who underwent CT examination of the lungs between 2010 and 2014. Two radiologists blinded to the presence of aspiration reviewed the images to detect the presence of any abnormality. Consensus was reached with a third radiologist. CT pulmonary findings (bronchial thickening, bronchiolectasis, centrilobular nodules, ground-glass opacities, atelectasis, consolidation and air trapping) were compared between the groups using the χ(2) test, with a significance level of 0.05.
resultsA total of 56 patients (28 patients with diagnoses of aspiration; 52% male, mean age 65 ± 15 years) were included in the study. Patients with aspiration were more likely to than those in the control group to demonstrate atelectasis, centrilobular nodules, bronchiolectasis, consolidation and ground-glass opacities (all p < 0.05), with a significant predilection for the lower lobes (p < 0.001). Bronchial wall thickening and air trapping did not differ between groups.
conclusionAtelectasis, centrilobular nodules, bronchiolectasis, consolidation and ground-glass opacities occurred more frequently in patients with aspiration than in those without aspiration, with a pronounced tendency for distribution in the lower lobes. ADVANCES IN KNOWLEDGE: CT findings of aspiration are very important, as pulmonary symptoms may be the first manifestation of this disorder. Knowledge of these findings is essential to enable the early diagnosis of aspiration disorders and prevent lung damage.
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