Evidence map›Paper›PMID 27225899›Full record

ArticlePlant physiology2016

Lack of GLYCOLATE OXIDASE1, but Not GLYCOLATE OXIDASE2, Attenuates the Photorespiratory Phenotype of CATALASE2-Deficient Arabidopsis.

Pavel Kerchev, Cezary Waszczak, Aleksandra Lewandowska, Patrick Willems, Alexey Shapiguzov, Zhen Li, Saleh Alseekh, Per Mühlenbock, Frank A Hoeberichts, Jingjing Huang and 7 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 118 citations in OpenAlex.

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  11. Transcriptome Analysis of Potato Leaves under Oxidative Stress.International journal of molecular sciences · 2024
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  15. Review
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  18. Reactive oxygen species signalling in plant stress responses.Nature reviews. Molecular cell biology · 2022
    Review
  19. Review
  20. HPR1 Is Required for High Light Intensity Induced Photorespiration inInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 6 countries.

Pavel KerchevDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).ORCID 0000-0003-2737-0493
Cezary WaszczakDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Aleksandra LewandowskaDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Patrick WillemsDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).ORCID 0000-0003-4667-2294
Alexey ShapiguzovDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Zhen LiDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).ORCID 0000-0001-8920-9270
Saleh AlseekhDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Per MühlenbockDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).ORCID 0000-0003-3097-8387
Frank A HoeberichtsDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Jingjing HuangDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Katrien Van Der KelenDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Jaakko KangasjärviDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).ORCID 0000-0002-8959-1809
Alisdair R FernieDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Riet De SmetDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Yves Van de PeerDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Joris MessensDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.).
Frank Van BreusegemDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S. Y.V.d.P., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (P.K., C.W., A.L., P.W., Z.L., P.M., F.A.H., K.V.D.K., R.D.S., Y.V.d.P., F.V.B.);Structural Biology Research Center, VIB, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Structural Biology Brussels Laboratory, Vrije Universiteit Brussel, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Brussels Center for Redox Biology, 1050 Brussels, Belgium (C.W., A.L., J.H., J.M.);Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, Helsinki FI-00014, Finland (C.W., A.S., J.K.);Institute of Plant Physiology, Russian Academy of Sciences, 127276 Moscow, Russia (A.S.);Max-Planck-Institute for Molecular Plant Physiology, 14476 Potsdam-Golm, Germany (S.A., A.R.F.);Distinguished Scientist Fellowship Program, College of Science, King Saud University, Riyadh, Saudi Arabia (J.K.); andGenomics Research Institute, University of Pretoria, Pretoria, South Africa (Y.V.d.P.) frank.vanbreusegem@psb.vib-ugent.be.ORCID 0000-0002-3147-0860
Ghent University · BEUniversity of Helsinki · FIVrije Universiteit Brussel · BEVIB-UGent Center for Plant Systems Biology · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genes coding for the core metabolic enzymes of the photorespiratory pathway that allows plants with C3-type photosynthesis to survive in an oxygen-rich atmosphere, have been largely discovered in genetic screens aimed to isolate mutants that are unviable under ambient air. As an exception, glycolate oxidase (GOX) mutants with a photorespiratory phenotype have not been described yet in C3 species. Using Arabidopsis (Arabidopsis thaliana) mutants lacking the peroxisomal CATALASE2 (cat2-2) that display stunted growth and cell death lesions under ambient air, we isolated a second-site loss-of-function mutation in GLYCOLATE OXIDASE1 (GOX1) that attenuated the photorespiratory phenotype of cat2-2 Interestingly, knocking out the nearly identical GOX2 in the cat2-2 background did not affect the photorespiratory phenotype, indicating that GOX1 and GOX2 play distinct metabolic roles. We further investigated their individual functions in single gox1-1 and gox2-1 mutants and revealed that their phenotypes can be modulated by environmental conditions that increase the metabolic flux through the photorespiratory pathway. High light negatively affected the photosynthetic performance and growth of both gox1-1 and gox2-1 mutants, but the negative consequences of severe photorespiration were more pronounced in the absence of GOX1, which was accompanied with lesser ability to process glycolate. Taken together, our results point toward divergent functions of the two photorespiratory GOX isoforms in Arabidopsis and contribute to a better understanding of the photorespiratory pathway.

Indexed as

Alcohol OxidoreductasesArabidopsisArabidopsis ProteinsCell RespirationEvolution, MolecularGlycolatesLightMetabolomeMutationOxidation-ReductionPhenotypePhotosynthesisAlcohol OxidoreductasesArabidopsis ProteinsGlycolatesglycollate oxidaseGox1 protein, Arabidopsis

Identifiers

PMID27225899
PMCPMC4936566
OpenAlexW2405022357

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.