Evidence map›Paper›PMID 27225862›Full record

ArticleThe Journal of international medical research2016

Assessment of serum chemerin, vaspin and omentin-1 levels in patients with polycystic ovary syndrome.

Yesim Guvenc, Ahmet Var, Asli Goker, Naci Kemal Kuscu

Abstract read
In one paragraph

Article in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Review of Novel Potential Insulin Resistance Biomarkers in PCOS Patients-The Debate Is Still Open.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yesim GuvencDepartment of Medical Biochemistry, Faculty of Medicine, Celal Bayar University, Manisa, Turkey yesim.guvenc@gmail.com.
Ahmet VarDepartment of Medical Biochemistry, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.
Asli GokerDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.
Naci Kemal KuscuDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine serum chemerin, vaspin and omentin-1 in overweight and normal weight patients with polycystic ovary syndrome (PCOS) and investigate the possible relationship between these adipokines and metabolic syndrome.

methodsThis cross sectional study enrolled women with PCOS and healthy women. Serum chemerin, vaspin and omentin-1 were assessed by enzyme-linked immunosorbent assay methods.

resultsForty patients with PCOS and 30 healthy controls were included in the study. In the PCOS group, 18 women were overweight (body mass index [BMI] = 25.0-29.9 kg/m(2)) and 22 had normal weight (BMI = 18.5-24.9 kg/m(2)). Chemerin, total cholesterol, dehydroepiandrosterone sulphate and free androgen index (FAI) were significantly higher; and high-density lipoprotein cholesterol and sex hormone binding globulin were significantly lower in overweight PCOS patients compared with normal weight PCOS patients. A positive correlation was found between chemerin and BMI, triglyceride, insulin, homeostatic model assessment of insulin resistance and FAI in the PCOS group. There was no difference in serum chemerin, vaspin and omentin-1 between PCOS patients and healthy controls.

conclusionCirculating chemerin was increased in overweight compared with normal weight PCOS patients. The most predictive variables for circulating chemerin in PCOS patients were BMI, FAI and age.

Indexed as

AdultCase-Control StudiesChemokinesCytokinesFemaleGPI-Linked ProteinsHumansIntercellular Signaling Peptides and ProteinsLectinsMultivariate AnalysisPolycystic Ovary SyndromeRegression AnalysisSerpinsChemokinesCytokinesGPI-Linked ProteinsIntercellular Signaling Peptides and ProteinsITLN1 protein, humanLectinsRARRES2 protein, humanSERPINA12 protein, humanSerpinsadipokineschemerinomentin-1Polycystic ovary syndromevaspin

Identifiers

PMID27225862
PMCPMC5536625

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.